View Item 

Show simple item record

Helicobacter pylori -induced atrophic gastritis progressing to gastric cancer exhibits sonic hedgehog loss and aberrant CDX2 expression

dc.contributor.authorShiotani, Akikoen_US
dc.contributor.authorIishi, Hiroyasuen_US
dc.contributor.authorUedo, N.en_US
dc.contributor.authorIshihara, R.en_US
dc.contributor.authorIshiguro, Shingoen_US
dc.contributor.authorTatsuta, Masaharuen_US
dc.contributor.authorNakae, Yukinorien_US
dc.contributor.authorKumamoto, M.en_US
dc.contributor.authorHinoi, T.en_US
dc.contributor.authorMerchant, Juanita L.en_US
dc.date.accessioned2010-06-01T19:02:03Z
dc.date.available2010-06-01T19:02:03Z
dc.date.issued2006-07en_US
dc.identifier.citationSHIOTANI, A.; IISHI, H.; UEDO, N.; ISHIHARA, R.; ISHIGURO, S.; TATSUTA, M.; NAKAE, Y.; KUMAMOTO, M.; HINOI, T.; MERCHANT, J. L. (2006). " Helicobacter pylori -induced atrophic gastritis progressing to gastric cancer exhibits sonic hedgehog loss and aberrant CDX2 expression." Alimentary Pharmacology & Therapeutics Symposium Series 2(1): 71-80. <http://hdl.handle.net/2027.42/72223>en_US
dc.identifier.issn1746-6334en_US
dc.identifier.issn1746-6342en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/72223
dc.format.extent426120 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights2006 The Authors Journal compilation 2006 Blackwell Publishing Ltden_US
dc.titleHelicobacter pylori -induced atrophic gastritis progressing to gastric cancer exhibits sonic hedgehog loss and aberrant CDX2 expressionen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelOtolaryngologyen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationum§ Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationother* Health Administration Center, Wakayama University, Wakayama, Japanen_US
dc.contributor.affiliationother† Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japanen_US
dc.contributor.affiliationother† Department of Internal Medicine Aishinkai Nakae Hospital, Wakayama, Japanen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/72223/1/j.1746-6342.2006.00028.x.pdf
dc.identifier.doi10.1111/j.1746-6342.2006.00028.xen_US
dc.identifier.sourceAlimentary Pharmacology & Therapeutics Symposium Seriesen_US
dc.identifier.citedreferenceCorrea P. Chronic gastritis as a cancer precursor. Scand J Gastroenterol Suppl 1984; 104: 131 – 6.en_US
dc.identifier.citedreferenceFilipe MI, Potet F, Bogomoletz WV, et al. Incomplete sulphomucin-secreting intestinal metaplasia for gastric cancer. Preliminary data from a prospective study from three centres. Gut 1985; 26: 1319 – 26.en_US
dc.identifier.citedreferenceEl-Zimaity HM, Ota H, Graham DY, Akamatsu T, Katsuyama T. Patterns of gastric atrophy in intestinal type gastric carcinoma. Cancer 2002; 94: 1428 – 36.en_US
dc.identifier.citedreferenceMatsuzaki H, Shimada S, Uno K, Tsuruta J, Ogawa M. Novel subtyping of intestinal metaplasia in the human stomach: brain-type glycogen phosphorylase expression in the proliferative zone and its relationship with carcinogenesis. Am J Clin Pathol 1998; 109: 181 – 9.en_US
dc.identifier.citedreferenceMatsukura N, Suzuki K, Kawachi T, et al. Distribution of marker enzymes and mucin in intestinal metaplasia in human stomach and relation to complete and incomplete types of intestinal metaplasia to minute gastric carcinomas. J Natl Cancer Inst 1980; 65: 231 – 40.en_US
dc.identifier.citedreferenceIida F, Kusama J. Gastric carcinoma and intestinal metaplasia. Significance of types of intestinal metaplasia upon development of gastric carcinoma. Cancer 1982; 50: 2854 – 8.en_US
dc.identifier.citedreferenceMeining A, Morgner A, Miehlke S, Bayerdorffer E, Stolte M. Atrophy–metaplasia–dysplasia–carcinoma sequence in the stomach: a reality or merely an hypothesis ? Best Pract Res Clin Gastroenterol 2001; 15: 983 – 98.en_US
dc.identifier.citedreferenceNusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980; 287: 795 – 801.en_US
dc.identifier.citedreferenceHammerschmidt M, Brook A, McMahon AP. The world according to hedgehog. Trends Genet 1997; 13: 14 – 21.en_US
dc.identifier.citedreferenceBitgood MJ, McMahon AP. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol 1995; 172: 126 – 38.en_US
dc.identifier.citedreferenceEchelard Y, Epstein DJ, St-Jacques B, et al. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993; 75: 1417 – 30.en_US
dc.identifier.citedreferenceRamalho-Santos M, Melton DA, McMahon AP. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 2000; 127: 2763 – 72.en_US
dc.identifier.citedreferenceLitingtung Y, Lei L, Westphal H, Chiang C. Sonic hedgehog is essential to foregut development. Nat Genet 1998; 20: 58 – 61.en_US
dc.identifier.citedreferencevan den Brink GR, Hardwick JC, Tytgat GN, et al. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology 2001; 121: 317 – 28.en_US
dc.identifier.citedreferencevan den Brink GR, Hardwick JC, Nielsen C, et al. Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract. Gut 2002; 51: 628 – 33.en_US
dc.identifier.citedreferenceShiotani A, Iishi H, Uedo N, et al. Evidence that loss of sonic hedgehog is an indicator of Helicobacter pylori-induced atrophic gastritis progressing to gastric cancer. Am J Gastroenterol 2005; 100: 581 – 7.en_US
dc.identifier.citedreferenceSilberg DG, Swain GP, Suh ER, Traber PG. Cdx1 and cdx2 expression during intestinal development. Gastroenterology 2000; 119: 961 – 71.en_US
dc.identifier.citedreferenceMacdonald PM, Struhl G. A molecular gradient in early Drosophila embryos and its role in specifying the body pattern. Nature 1986; 324: 537 – 45.en_US
dc.identifier.citedreferenceMoreno E, Morata G. Caudal is the Hox gene that specifies the most posterior Drosophile segment. Nature 1999; 400: 873 – 7.en_US
dc.identifier.citedreferenceBeck F, Chawengsaksophak K, Waring P, Playford RJ, Furness JB. Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice. Proc Natl Acad Sci U S A 1999; 96: 7318 – 23.en_US
dc.identifier.citedreferencePhillips RW, Frierson HF Jr, Moskaluk CA. Cdx2 as a marker of epithelial intestinal differentiation in the esophagus. Am J Surg Pathol 2003; 27: 1442 – 7.en_US
dc.identifier.citedreferenceSilberg DG, Sullivan J, Kang E, et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology 2002; 122: 689 – 96.en_US
dc.identifier.citedreferenceMatsumoto K, Mizoshita T, Tsukamoto T, et al. Cdx2 expression in pancreatic tumors: Relationship with prognosis of invasive ductal carcinomas. Oncol Rep 2004; 12: 1239 – 43.en_US
dc.identifier.citedreferencePiscitelli D, Ingravallo G, Resta L, Fiore MG, Maiorano E. Oncocytic adenocarcinoma of the rectum with diffuse intra-luminal microcalcifications: the first reported case. Virchows Arch 2003; 443: 579 – 82.en_US
dc.identifier.citedreferenceKaimaktchiev V, Terracciano L, Tornillo L, et al. The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas. Mod Pathol 2004; 17: 1392 – 9.en_US
dc.identifier.citedreferenceMizoshita T, Tsukamoto T, Nakanishi H, et al. Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol 2003; 129: 727 – 34.en_US
dc.identifier.citedreferenceSeno H, Oshima M, Taniguchi MA, et al. CDX2 expression in the stomach with intestinal metaplasia and intestinal-type cancer: prognostic implications. Int J Oncol 2002; 21: 769 – 74.en_US
dc.identifier.citedreferenceDixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996; 20: 1161 – 81.en_US
dc.identifier.citedreferenceMutoh H, Sakurai S, Satoh K, et al. Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice. Cancer Res 2004; 64: 7740 – 7.en_US
dc.identifier.citedreferenceSeregni E, Botti C, Massaron S, et al. Structure, function and gene expression of epithelial mucins. Tumori 1997; 83: 625 – 32.en_US
dc.identifier.citedreferenceTsukamoto T, Inada K, Tanaka H, et al. Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia. J Cancer Res Clin Oncol 2004; 130: 135 – 45.en_US
dc.identifier.citedreferenceOldak M, Grzela T, Lazarczyk M, Malejczyk J, Skopinski P. Clinical aspects of disrupted Hedgehog signaling (review). Int J Mol Med 2001; 8: 445 – 52.en_US
dc.identifier.citedreferenceFaller G, Kirchner T. Immunological and morphogenic basis of gastric mucosa atrophy and metaplasia. Virchows Arch 2005; 446: 1 – 9.en_US
dc.identifier.citedreferenceJacob J, Briscoe J. Gli proteins and the control of spinal-cord patterning. EMBO Rep 2003; 4: 761 – 5.en_US
dc.identifier.citedreferenceFukamachi H, Ito K, Ito Y. Runx3-/- gastric epithelial cells differentiate into intestinal type cells. Biochem Biophys Res Commun 2004; 321: 58 – 64.en_US
dc.identifier.citedreferenceHinoi T, Lucas PC, Kuick R, Hanash S, Cho KR, Fearon ER. CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology 2002; 123: 1565 – 77.en_US
dc.identifier.citedreferenceShiotani A, Iishi H, Kumamoto M, Nakae Y. Helicobacter pylori infection and increased nitrite synthesis in the stomach. Inflammation and atrophy connections. Dig Liver Dis 2004; 36: 327 – 32.en_US
dc.identifier.citedreferenceShiotani A, Iishi H, Uedo N, et al. Hypoacidity combined with high gastric juice nitrite induced by Helicobacter pylori infection is associated with gastric cancer. Aliment Pharmacol Ther 2004; 20 ( Suppl 1 ): 48 – 53.en_US
dc.identifier.citedreferenceDimmler A, Brabletz T, Hlubek F, et al. Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions. Lab Invest 2003; 83: 1829 – 37.en_US
dc.identifier.citedreferenceFaller G, Dimmler A, Rau T, et al. Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia. J Pathol 2004; 203: 904 – 8.en_US
dc.identifier.citedreferenceSatoh K, Mutoh H, Eda A, et al. Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. Helicobacter 2002; 7: 192 – 8.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
j.1746-6342.2006.00028.x.pdf
Size:
416.1KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.