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The utility of diagnostic tests in irritable bowel syndrome patients: a systematic review

dc.contributor.authorCash, Brooks D.en_US
dc.contributor.authorSchoenfeld, Philip S.en_US
dc.contributor.authorChey, William D.en_US
dc.date.accessioned2010-06-01T19:22:05Z
dc.date.available2010-06-01T19:22:05Z
dc.date.issued2002-11en_US
dc.identifier.citationCash, Brooks D . ; Schoenfeld, Philip; Chey, William D . (2002). "The utility of diagnostic tests in irritable bowel syndrome patients: a systematic review." The American Journal of Gastroenterology 97(11): 2812-2819. <http://hdl.handle.net/2027.42/72511>en_US
dc.identifier.issn0002-9270en_US
dc.identifier.issn1572-0241en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/72511
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12425553&dopt=citationen_US
dc.description.abstractThe aim of this study was to determine the pretest probability of organic GI disease and the accuracy of diagnostic tests for organic GI disease in patients who meet symptom-based criteria for irritable bowel syndrome (IBS). METHODS : After a comprehensive literature search for studies examining the accuracy of diagnostic tests for organic GI disease among patients who meet symptom-based criteria for IBS, two independent observers qualitatively assessed the methodology of selected studies and extracted data. Data on the pretest probability of organic GI disease in this population and the accuracy of currently recommended diagnostic tests were converted to descriptive tables. RESULTS : Among patients meeting symptom-based criteria for IBS, the pretest probability of inflammatory bowel disease, colorectal cancer, or infectious diarrhea is less than 1%. Currently recommended diagnostic tests rarely identify organic GI disease in patients fulfilling symptom-based criteria for IBS. However, the pretest probability of celiac disease in patients meeting symptom-based criteria for IBS was 10 times higher than the prevalence of celiac disease in the general population. CONCLUSION : There is insufficient evidence to recommend the routine performance of a standardized battery of diagnostic tests in patients who meet symptom-based criteria for IBS. Based upon the increased pretest probability of celiac disease, routine performance of serological tests for celiac disease may be useful in this patient population, though additional study is needed in this area.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights2002 by Am. Coll. of Gastroenterologyen_US
dc.titleThe utility of diagnostic tests in irritable bowel syndrome patients: a systematic reviewen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Gastroenterology, University of Michigan School of Medicine, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumVA Center for Excellence in Health Care Research, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationotherDivision of Gastroenterology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USAen_US
dc.identifier.pmid12425553en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/72511/1/j.1572-0241.2002.07027.x.pdf
dc.identifier.doi10.1111/j.1572-0241.2002.07027.xen_US
dc.identifier.sourceThe American Journal of Gastroenterologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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