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FIP1L1/PDGFRA is a molecular marker of chronic eosinophilic leukaemia but not for systemic mastocytosis

dc.contributor.authorValent, P.en_US
dc.contributor.authorAkin, C.en_US
dc.contributor.authorMetcalfe, D. D.en_US
dc.date.accessioned2010-06-01T19:37:07Z
dc.date.available2010-06-01T19:37:07Z
dc.date.issued2007-02en_US
dc.identifier.citationValent, P.; Akin, C.; Metcalfe, D. D. (2007). "FIP1L1/PDGFRA is a molecular marker of chronic eosinophilic leukaemia but not for systemic mastocytosis." European Journal of Clinical Investigation 37(2): 153-154. <http://hdl.handle.net/2027.42/72754>en_US
dc.identifier.issn0014-2972en_US
dc.identifier.issn1365-2362en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/72754
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17217382&dopt=citationen_US
dc.format.extent58116 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights© 2007 The Authors. Journal Compilation © 2007 Blackwell Publishing Ltden_US
dc.titleFIP1L1/PDGFRA is a molecular marker of chronic eosinophilic leukaemia but not for systemic mastocytosisen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Allergy and Immunology, University of Michigan, Ann Arbor, MI, USA,en_US
dc.contributor.affiliationotherDivision of Haematology & Haemostaseology, Medical University of Vienna, Vienna, Austria,en_US
dc.contributor.affiliationotherLaboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USAen_US
dc.identifier.pmid17217382en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/72754/1/j.1365-2362.2007.01757.x.pdf
dc.identifier.doi10.1111/j.1365-2362.2007.01757.xen_US
dc.identifier.sourceEuropean Journal of Clinical Investigationen_US
dc.identifier.citedreferenceBain B, Pierre R, Imbert M, Vardiman JW, Brunning RD, Flandrin G. Chronic eosinophilic leukemia and hypereosinophilic syndrome. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization (WHO) Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press, 2001, pp. 29 – 31.en_US
dc.identifier.citedreferenceGotlib J, Cools J, Malone JM, Schrier SL, Gilliland DG, Coutre SE. The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management. Blood 2004; 103: 2879 – 91.en_US
dc.identifier.citedreferencePardanani A, Ketterling RP, Brockman SR, Flynn HC, Paternoster SF, Shearer BM et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood 2003; 102: 3093 – 6.en_US
dc.identifier.citedreferenceTravis WD, Li CY, Yam LT, Bergstralh EJ, Swee RG. Significance of systemic mast cell disease with associated hematologic disorders. Cancer 1988; 62: 965 – 72.en_US
dc.identifier.citedreferenceHorny H-P, Ruck M, Wehrmann M, Kaiserling E. Blood findings in generalized mastocytosis: evidence of frequent simultaneous occurrence of myeloproliferative disorders. Br J Haematol 1990; 76: 186 – 93.en_US
dc.identifier.citedreferenceMetcalfe DD. Classification and diagnosis of mastocytosis: current status. J Invest Dermatol 1991; 96: 2S – 4S.en_US
dc.identifier.citedreferenceNagata H, Worobec AS, Oh CK, Chowdhury BA, Tannenbaum S, Suzuki Y et al. Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci USA 1995; 92: 10560 – 4.en_US
dc.identifier.citedreferenceSotlar K, Marafioti T, Griesser H, Theil J, Aepinus C, Jaussi R et al. Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia. Mol Pathol 2000; 53: 188 – 93.en_US
dc.identifier.citedreferenceValent P, Horny HP, Escribano L, Longley BJ, Li CY, Schwartz LB et al. Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res 2001; 25: 603 – 25.en_US
dc.identifier.citedreferenceValent P, Horny H-P, Li CY, Longley JB, Metcalfe DD, Parwaresch RM et al. Mastocytosis (Mast cell disease). In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization (WHO) Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press, 2001, pp. 291 – 302.en_US
dc.identifier.citedreferenceValent P, Ghannadan M, Akin C, Krauth MT, Selzer E, Mayerhofer M et al. On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts. Eur J Clin Invest 2004; 34 ( S2 ): 41 – 52.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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