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Treatment of Malignant Fibrous Histiocytoma and Atypical Fibrous Xanthomas with Micrographic Surgery

dc.contributor.authorBrown, Marc D.en_US
dc.contributor.authorSwanson, Neil A.en_US
dc.date.accessioned2010-06-01T20:10:29Z
dc.date.available2010-06-01T20:10:29Z
dc.date.issued1989-12en_US
dc.identifier.citationBROWN, MARC D.; SWANSON, NEIL A. (1989). "Treatment of Malignant Fibrous Histiocytoma and Atypical Fibrous Xanthomas with Micrographic Surgery." The Journal of Dermatologic Surgery and Oncology 15(12): 1287-1293. <http://hdl.handle.net/2027.42/73298>en_US
dc.identifier.issn0148-0812en_US
dc.identifier.issn1524-4725en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73298
dc.description.abstractFibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery for the treatment of DFSP, but data have been lacking on the potential benefit of this surgical approach for MFH and AFX tumors. Over the past 6 years, we have treated 17 patients with MFH (20 tumors) and 5 patients with AFX with Mohs micrographic surgery. A retrospective analysis of the surgical results is presented. To date (average 3-year follow-up), all patients contacted are tumor free with only one recurrence; no patient has developed metastatic disease. Our results to date are very encouraging; they lend support to Mohs micrographic surgery as a desired surgical approach for these diffiult-to-cure neoplasms.en_US
dc.format.extent832522 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1989 American Society for Dermatologic Surgery, Inc.en_US
dc.titleTreatment of Malignant Fibrous Histiocytoma and Atypical Fibrous Xanthomas with Micrographic Surgeryen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelDermatologyen_US
dc.subject.hlbsecondlevelOncology and Hematologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMarc D. Brown, M.D., and Neil A. Swanson, M.D., Associate Professor of Dermatology, Department of Dermatology, are from the University of Michigan Medical Center, Ann Arbor, Michigan.en_US
dc.identifier.pmid2556464en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73298/1/j.1524-4725.1989.tb03149.x.pdf
dc.identifier.doi10.1111/j.1524-4725.1989.tb03149.xen_US
dc.identifier.sourceThe Journal of Dermatologic Surgery and Oncologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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