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Mucous membrane and lower respiratory building related symptoms in relation to indoor carbon dioxide concentrations in the 100-building BASE dataset
dc.contributor.authorErdmann, C. A.en_US
dc.contributor.authorApte, Michael G.en_US
dc.date.accessioned2010-06-01T20:19:19Z
dc.date.available2010-06-01T20:19:19Z
dc.date.issued2004-12en_US
dc.identifier.citationErdmann, Christine A.; Apte, Michael G. (2004). "Mucous membrane and lower respiratory building related symptoms in relation to indoor carbon dioxide concentrations in the 100-building BASE dataset." Indoor Air 14(s8): 127-134. <http://hdl.handle.net/2027.42/73439>en_US
dc.identifier.issn0905-6947en_US
dc.identifier.issn1600-0668en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73439
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15663468&dopt=citationen_US
dc.description.abstractIndoor air pollutants are a potential cause of building related symptoms and can be reduced by increasing ventilation rates. Indoor carbon dioxide (CO 2 ) concentration is an approximate surrogate for concentrations of occupant-generated pollutants and for ventilation rate per occupant. Using the US EPA 100 office-building BASE Study dataset, we conducted multivariate logistic regression analyses to quantify the relationship between indoor CO 2 concentrations (dCO 2 ) and mucous membrane (MM) and lower respiratory system (LResp) building related symptoms, adjusting for age, sex, smoking status, presence of carpet in workspace, thermal exposure, relative humidity, and a marker for entrained automobile exhaust. In addition, we tested the hypothesis that certain environmentally mediated health conditions (e.g., allergies and asthma) confer increased susceptibility to building related symptoms. Adjusted odds ratios (ORs) for statistically significant, dose–dependent associations ( P <  0.05) for combined mucous membrane, dry eyes, sore throat, nose/sinus congestion, sneeze, and wheeze symptoms with 100 p.p.m. increases in dCO 2 ranged from 1.1 to 1.2. Building occupants with certain environmentally mediated health conditions were more likely to report that they experience building related symptoms than those without these conditions (statistically significant ORs ranged from 1.5 to 11.1, P  < 0.05).en_US
dc.format.extent177743 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishingen_US
dc.rights2004 Blackwell Munksgaarden_US
dc.subject.otherBASE Studyen_US
dc.subject.otherCarbon Dioxideen_US
dc.subject.otherIndoor Environmental Qualityen_US
dc.subject.otherBuilding Related Symptomsen_US
dc.subject.otherSick Building Syndromeen_US
dc.subject.otherVentilationen_US
dc.titleMucous membrane and lower respiratory building related symptoms in relation to indoor carbon dioxide concentrations in the 100-building BASE dataseten_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumAssistant Professor, University of Michigan, Department of Epidemiology, School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109-2029, USAen_US
dc.contributor.affiliationotherStaff Scientist, Mailstop 90R3058, Indoor Environment Department, Lawrence Berkeley National Laboratory, One Cyclotron Road, Berkeley, CA 94720, USAen_US
dc.identifier.pmid15663468en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73439/1/j.1600-0668.2004.00298.x.pdf
dc.identifier.doi10.1111/j.1600-0668.2004.00298.xen_US
dc.identifier.sourceIndoor Airen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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