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SERUM LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE IN NORMAL CHILDREN AND PATIENTS WITH VARIOUS CLINICAL DISORDERS
dc.contributor.authorLee, Peter A.en_US
dc.date.accessioned2010-06-01T20:29:22Z
dc.date.available2010-06-01T20:29:22Z
dc.date.issued1973-07en_US
dc.identifier.citationLEE, PETER A. (1973). "SERUM LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE IN NORMAL CHILDREN AND PATIENTS WITH VARIOUS CLINICAL DISORDERS." Clinical Endocrinology 2(3): 255-264. <http://hdl.handle.net/2027.42/73601>en_US
dc.identifier.issn0300-0664en_US
dc.identifier.issn1365-2265en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/73601
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4148555&dopt=citationen_US
dc.description.abstractSerum concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were determined in 329 normal children and 185 individuals with endocrinological abnormalities or variations of development. A significant increase of gonadotrophins is noted at the onset of puberty among the boys and at menarche for girls. The values are compared with serum concentrations of LH and FSH in children with abnormalities of sexual development, pituitary malfunction as well as other clinical abnormalities. Comparable levels for age and stage of development were found for premature thelarche, premature adrenarche, cryptorchidism, male pseudohermaphroditism and pubertal gynaecomastia. Hypogonadal individuals (Klinefelter's and Turner's syndrome, pure ovarian dysgenesis and testicular dysgenesis) have markedly elevated values while those with pituitary hypofunction had low values. Patients with sexual prococity tended to have elevated concentrations.en_US
dc.format.extent584097 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1973 Blackwell Scientific Publicationsen_US
dc.titleSERUM LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE IN NORMAL CHILDREN AND PATIENTS WITH VARIOUS CLINICAL DISORDERSen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pediatrics and The Reproductive Endocrinology Program, Departments of Pathology and Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid4148555en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/73601/1/j.1365-2265.1973.tb00427.x.pdf
dc.identifier.doi10.1111/j.1365-2265.1973.tb00427.xen_US
dc.identifier.sourceClinical Endocrinologyen_US
dc.identifier.citedreferenceBurr, I.M., Sizonenko, P.C., Kaplan, S.L. & Grumbach, M.M. ( 1970 ) Hormonal changes in puberty. I. Correlation of serum luteinizing hormone and follicle stimulating hormone with stages of puberty, testicular size, and bone age in normal boys. Pediatric Research, 4, 25.en_US
dc.identifier.citedreferenceFaiman, C. & Winter, J.S.D. ( 1971 ) Sex differences in gonadotropin concentrations in infancy. Nature, 232, 130.en_US
dc.identifier.citedreferenceGuyda, H.J., Johanson, A.J., Migeon, C.J. & Blizzard, R.M. ( 1969 ) Determination of serum luteinizing hormone (SLH) by radioimmunoassay in disorders of adolescent sexual development. Pediatric Research, 3, 538.en_US
dc.identifier.citedreferenceJenner, M.R., Kelch, R.P., Kaplan, S.L. & Grumbach, M.M. ( 1972 ) Hormonal changes in puberty. IV. Plasma estradiol, LH and FSH in prepubertal children, pubertal females, and in precocious puberty, premature thelarche, hypogonadism, and in a child with a feminizing ovarian tumor. Journal of Clinical Endocrinology and Metabolism, 34, 521.en_US
dc.identifier.citedreferenceJohanson, A.J., Guyda, H.J., Light, C., Migeon, C.J. & Blizzard, R.M. ( 1969 ) Serum luteinizing hormone by radioimmunoassay in normal children. Journal of Pediatrics, 74, 416.en_US
dc.identifier.citedreferenceKenny, F.M., Midgley, A.R., Jr, Jaffe, R.B., Garces, L.Y., Vazquez, A. & Taylor, F.H. ( 1969 ) Radioimmunoassayable serum LH and FSH in girls with sexual precocity, premature thelarche and adrenarche. Journal of Clinical Endocrinology and Metabolism, 29, 1272.en_US
dc.identifier.citedreferenceLee, P.A., Middgley, A.R., Jr & Jaffe, R.B. ( 1970 ) Regulation of human gonadotropins. VI. Serum follicle stimulating and luteinizing hormone determinations in children. Journal of Clinical Endocrinology and Metabolism, 31, 248.en_US
dc.identifier.citedreferenceMidgley, A.R., Jr & Reichert, L.E. ( 1969 ) Specificity studies on a radioimmunoassay for human follicle stimulating hormone. Protein and Polypeptide Hormones ( Ed. Margoulies ), p. 117. Excerpta Medica Foundation, Amsterdam.en_US
dc.identifier.citedreferenceMidgley, A.R., Jr, Fong, I.F. & Jaffe, R.B. ( 1967 ) Gel filtration radioimmunoassay to distinguish human chorionic gonadotropin from luteinizing hormone. Nature, 213, 733.en_US
dc.identifier.citedreferencePaulsen, C.A., Gordon, D.L., Carpenter, R.W., Gandy, H.M. & Drucker, W.D. ( 1968 ) Klinefelter's syndrome and its variants: A hormonal and chromosomal study. Recent Progress in Hormone Research, 24, 321.en_US
dc.identifier.citedreferencePenny, R., Guyda, H.J., Baghdassarian, A., Johanson, A.J. & Blizzard, R.M. ( 1970 ) Correlation of serum follicular stimulating hormone (FSH) and luteinizing hormone (LH) as measured by radioimmunoassay in disorders of sexual development. Journal of Clinical Investigation, 49, 1847.en_US
dc.identifier.citedreferencePierce, J.G., Bahl, O.P., Cornell, J.S. & Swaminathan, N. ( 1971 ) Biologically active hormones prepared by recombination of the alpha chain of human chorionic gonadotropin and the hormone specific chain of bovine thyrotropin or of bovine luteinizing hormone. Journal of Biological Chemistry, 246, 2321.en_US
dc.identifier.citedreferenceRaiti, S., Johanson, A.J., Light, C., Migeon, C.J. & Blizzard, R.M. ( 1969 ) Measurement of immunologically reactive follicle stimulating hormone in serum of normal male children and adults. Metabolism, 18, 234.en_US
dc.identifier.citedreferenceRathnam, P. & Saxena, B.B. ( 1971 ) Subunits of luteinizing hormone from human pituitary glands. Journal of Biological Chemistry, 246, 7087. F.en_US
dc.identifier.citedreferenceRoot, A.W., Moshang, T., Jr, Bongiovanni, A.M. & Eberlein, W.R. ( 1970 ) Concentrations of plasma luteinizing hormone in infants, children and adolescents with normal and abnormal gonadal functions. Pediatric Research, 4, 175.en_US
dc.identifier.citedreferenceSaxena, B.B., Demura, H., Gandy, H.M. & Peterson, R.E. ( 1968 ) Radioimmunoassay of human follicle stimulating and luteinizing hormones in plasma. Journal of Clinical Endocrinology and Metabolism, 28, 519.en_US
dc.identifier.citedreferenceSizonenko, P.C., Burr, I.M., Kaplan, S.L. & Grumbach, M.M. ( 1970 ) Hormonal changes in puberty. II. Correlation of serum luteinizing hormone with stages of puberty and bone age in girls. Pediatric Research, 4, 36.en_US
dc.identifier.citedreferenceTanner, J.M. ( 1962 ) Growth at Adolescence, 2nd edn. Blackwell Scientific Publications, Oxford.en_US
dc.identifier.citedreferenceTremblay, R.R., Foley, T.P., Jr, Corvol, P., Park, I.J., Kowarski, A., Blizzard, R.M., Jones, H.W., Jr & Migeon, C.J. ( 1972 ) Plasma concentrations of testosterone, dihydrotestosterone, testosteroneoestradiol binding globulin and pituitary gonadotropins in the syndrome of male pseudohermaphroditism with testicular feminization. Acta Endocrinologica, 70, 331.en_US
dc.identifier.citedreferenceWinter, J.S.D. & Faiman, C. ( 1972 ) Pituitary-gonadal relations in male children and adolescents. Pediatric Research, 6, 126.en_US
dc.identifier.citedreferenceYen, S.S.C. & Vicic, W.J. ( 1970 ) Serum follicle stimulating hormone levels in puberty. American Journal of Obstetrics and Gynecology, 106, 134.en_US
dc.identifier.citedreferenceYen, S.S.C., Vicic, W.J. & Kearchner, D.V. ( 1969 ) Gonadotropin levels in puberty. I. Serum luteinizing hormone. Journal of Clinical Endocrinology and Metabolism, 29, 382.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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