Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization
dc.contributor.author | Beauregard, Kathryn E. | en_US |
dc.contributor.author | Collier, R. John | en_US |
dc.contributor.author | Swanson, Joel A. | en_US |
dc.date.accessioned | 2010-06-01T20:56:48Z | |
dc.date.available | 2010-06-01T20:56:48Z | |
dc.date.issued | 2000-06 | en_US |
dc.identifier.citation | Beauregard, Kathryn E.; Collier, R. John; Swanson, Joel A. (2000). "Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization." Cellular Microbiology 2(3): 251-258. <http://hdl.handle.net/2027.42/74041> | en_US |
dc.identifier.issn | 1462-5814 | en_US |
dc.identifier.issn | 1462-5822 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/74041 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11207581&dopt=citation | en_US |
dc.format.extent | 441213 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Science Ltd | en_US |
dc.rights | Blackwell Science Ltd | en_US |
dc.title | Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109–0620, USA. | en_US |
dc.contributor.affiliationother | Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA. | en_US |
dc.identifier.pmid | 11207581 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/74041/1/j.1462-5822.2000.00052.x.pdf | |
dc.identifier.doi | 10.1046/j.1462-5822.2000.00052.x | en_US |
dc.identifier.source | Cellular Microbiology | en_US |
dc.identifier.citedreference | Ballard, J.D., Doling, A.M., Beauregard, K., Collier, R.J., Starnbach, M.N. ( 1998 ) Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin. Infect Immun 66: 615 619. | en_US |
dc.identifier.citedreference | Beauregard, K.E., Wimer-Mackin, S., Collier, R.J., Lencer, W.I. ( 1999 ) Anthrax toxin entry into polarized epithelial cells. Infect Immun 67: 3026 3030. | en_US |
dc.identifier.citedreference | Duesbery, N.S., Webb, C.P., Leppla, S.H., Gordon, V.M., Klimpel, K.R., Copeland, T.D., Ahn, N.G., Oskarsson, M.K., Fukasawa, K., Paull, K.D., Woude, G.F.V. ( 1998 ) Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 280: 734 737. | en_US |
dc.identifier.citedreference | Escuyer, V. & Collier, R.J. ( 1991 ) Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells. Infect Immun 59: 3381 3386. | en_US |
dc.identifier.citedreference | Friedlander, A.M. ( 1986 ) Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem 261: 7123 7126. | en_US |
dc.identifier.citedreference | Fujimoto, T. ( 1996 ) GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking. J Histochem Cytochem 44: 929 941. | en_US |
dc.identifier.citedreference | Gill, D.M. ( 1978 ) Seven toxic peptides that cross cell membranes. In: Bacterial Toxins and Cell Membranes, Jeljaszewicz, J. and Wadstrom, T. (eds). New York: Academic Press, pp. 291 332. | en_US |
dc.identifier.citedreference | Gordon, V.M., Leppla, S.H., Hewlitt, E.L. ( 1988 ) Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect Immun 56: 1066 1069. | en_US |
dc.identifier.citedreference | Gordon, V.M., Klimpel, K.R., Arora, N., Henderson, M.A., Leppla, S.H. ( 1995 ) Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect Immun 63: 82 87. | en_US |
dc.identifier.citedreference | Hanna, P.C., Acosta, D., Collier, R.J. ( 1993 ) On the role of macrophages in anthrax. Proc Natl Acad Sci USA 90: 10198 10201. | en_US |
dc.identifier.citedreference | Hopkins, C.R., Gibson, A., Shipman, M., Miller, K. ( 1990 ) Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum. Nature 346: 335 339. | en_US |
dc.identifier.citedreference | King, A.C. & Cuatrecasas, P. ( 1981 ) Peptide hormone-induced receptor mobility, aggregation, and internalization. N Engl J Med 305: 77 88. | en_US |
dc.identifier.citedreference | Klimpel, K.R., Molloy, S.S., Thomas, G., Leppla, S.H. ( 1992 ) Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proc Natl Acad Sci USA 89: 10277 10281. | en_US |
dc.identifier.citedreference | Kochi, S.K., Martin, I., Schiavo, G., Mock, M., Cabiaux, V. ( 1994 ) The effects of pH on the interaction of anthrax toxin lethal and edema factors with phospholipid vesicles. Biochemistry 33: 2604 2609. | en_US |
dc.identifier.citedreference | Leppla, S.H. ( 1982 ) Anthrax toxin edema factor: a bacterial adenylate cyclase that increase cAMP concentrations in eukaryotic cells. Proc Natl Acad Sci USA 79: 3162 3166. | en_US |
dc.identifier.citedreference | Leppla, S.H. ( 1991 ) The Anthrax Toxin Complex. San Diego: Academic Press, pp. 277 302. | en_US |
dc.identifier.citedreference | Mayor, S., Rothberg, K.G., Maxfield, F.R. ( 1994 ) Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264: 1948 1951. | en_US |
dc.identifier.citedreference | Menard, A., Altendorf, K., Breves, D., Mock, M., Montecucco, C. ( 1996 ) The vacuolar ATPase proton pump is required for the cytotoxicity of Bacillus anthracis lethal toxin. FEBS Lett 386: 161 164. | en_US |
dc.identifier.citedreference | Milne, J.C., Furlong, D., Hanna, P.C., Wall, J.S., Collier, R.J. ( 1994 ) Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem 269: 20607 20612. | en_US |
dc.identifier.citedreference | Molloy, S.S., Thomas, L., VanSlyke, J.K., Stenberg, P.E., Thomas, G. ( 1994 ) Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J 13: 18 33. | en_US |
dc.identifier.citedreference | Novak, J.M., Stein, M.-P., Little, S.F., Leppla, S.H., Friedlander, A.M. ( 1992 ) Functional characterization of protease-treated Bacillus anthracis protective antigen. J Biol Chem 267: 17186 17193. | en_US |
dc.identifier.citedreference | Parton, R.G. ( 1994 ) Ultrastructural localization of gangliosides: GM1 is concentrated in caveolae. J Histochem Cytochem 42: 155 166. | en_US |
dc.identifier.citedreference | Racoosin, E.L. & Swanson, J.A. ( 1992 ) M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages. J Cell Sci 102: 867 880. | en_US |
dc.identifier.citedreference | Singh, Y., Chaudhary, V.K., Leppla, S.H. ( 1989 ) A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J Biol Chem 264: 19103 19107. | en_US |
dc.identifier.citedreference | Singh, Y., Klimpel, K.R., Goel, S., Swain, P.K., Leppla, S.H. ( 1999 ) Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells. Infect Immun 67: 1853 1859. | en_US |
dc.identifier.citedreference | Swanson, J.A. ( 1989 ) Phorbol esters stimulate macropinocytosis and solute flow through macrophages. J Cell Sci 94: 135 142. | en_US |
dc.identifier.citedreference | Wang, X.-M., Mock, M., Ruysschaert, J.-M., Cabiaux, V. ( 1996 ) Secondary structure of anthrax lethal proteins and their interaction with large unilamellar vesicle: a Fourier-transform infrared spectroscopy approach. Biochemistry 35: 14939 14946. | en_US |
dc.identifier.citedreference | Wang, X.-M., Wattiez, R., Mock, M. ( 1997 ) Structure and Interaction of PA63 and EF (Edema Toxin) of Bacillus anthracis with lipid membrane. Biochemistry 36: 14906 14903. | en_US |
dc.identifier.citedreference | Watts, C. ( 1985 ) Rapid endocytosis of the transferrin receptor in the absence of bound transferrin. J Cell Biol 100: 633 637. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.