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Mycobacterium chelonae necrotizing pneumonia after allogeneic hematopoietic stem cell transplant: report of clinical response to treatment with tigecycline

dc.contributor.authorPeres, E.en_US
dc.contributor.authorKhaled, Y.en_US
dc.contributor.authorKrijanovski, O. I.en_US
dc.contributor.authorMineishi, S.en_US
dc.contributor.authorLevine, John E.en_US
dc.contributor.authorKaul, D. R.en_US
dc.contributor.authorRiddell, Jamesen_US
dc.date.accessioned2010-06-01T21:01:25Z
dc.date.available2010-06-01T21:01:25Z
dc.date.issued2009-02en_US
dc.identifier.citationPeres, E.; Khaled, Y.; Krijanovski, O.I.; Mineishi, S.; Levine, J.E.; Kaul, D.R.; Riddell, J. (2009). " Mycobacterium chelonae necrotizing pneumonia after allogeneic hematopoietic stem cell transplant: report of clinical response to treatment with tigecycline." Transplant Infectious Disease 11(1): 57-63. <http://hdl.handle.net/2027.42/74115>en_US
dc.identifier.issn1398-2273en_US
dc.identifier.issn1399-3062en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74115
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18983415&dopt=citationen_US
dc.description.abstractWe present a case of progressive Mycobacterium chelonae ssp. chelonae necrotizing pneumonia after hematopoietic stem cell transplantation (HSCT) in the presence of chronic graft-versus-host disease. The patient failed to respond to standard combination therapy with multiple agents and developed resistance to most drugs over the course of treatment. Tigecycline, a new glycylcycline antimicrobial agent with in vitro activity against M. chelonae , was then used with a clinical response to treatment. To our knowledge, this is the first reported case demonstrating tigecycline to have a degree of clinical effectiveness to treat refractory pulmonary infection with M. chelonae in an HSCT recipient.en_US
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dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Incen_US
dc.rights© 2009 John Wiley & Sons A/Sen_US
dc.subject.otherStem Cell Transplanten_US
dc.subject.otherNon-tuberculous Mycobacteriumen_US
dc.subject.otherPneumoniaen_US
dc.subject.otherTigecyclineen_US
dc.subject.otherMycobacterium Chelonaeen_US
dc.titleMycobacterium chelonae necrotizing pneumonia after allogeneic hematopoietic stem cell transplant: report of clinical response to treatment with tigecyclineen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbsecondlevelMicrobiology and Immunologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumBlood and Marrow Transplant Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA , anden_US
dc.contributor.affiliationumDivision of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid18983415en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74115/1/j.1399-3062.2008.00351.x.pdf
dc.identifier.doi10.1111/j.1399-3062.2008.00351.xen_US
dc.identifier.sourceTransplant Infectious Diseaseen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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