Overt Diabetic Neuropathy: Repair of Axo-glial Dysjunction and Axonal Atrophy by Aldose Reductase Inhibition and its Correlation to Improvement in Nerve Conduction Velocity
dc.contributor.author | Sima, Anders A. F. | en_US |
dc.contributor.author | Prashar, A. | en_US |
dc.contributor.author | Nathaniel, V. | en_US |
dc.contributor.author | Bril, Vera | en_US |
dc.contributor.author | Werb, M. R. | en_US |
dc.contributor.author | Greene, Douglas A. | en_US |
dc.date.accessioned | 2010-06-01T21:04:57Z | |
dc.date.available | 2010-06-01T21:04:57Z | |
dc.date.issued | 1993-03 | en_US |
dc.identifier.citation | Sima, A.A.F.; Prashar, A.; Nathaniel, V.; Bril, V.; Werb, M.R.; Greene, D.A. (1993). "Overt Diabetic Neuropathy: Repair of Axo-glial Dysjunction and Axonal Atrophy by Aldose Reductase Inhibition and its Correlation to Improvement in Nerve Conduction Velocity." Diabetic Medicine 10(2): 115-121. <http://hdl.handle.net/2027.42/74171> | en_US |
dc.identifier.issn | 0742-3071 | en_US |
dc.identifier.issn | 1464-5491 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/74171 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8458187&dopt=citation | en_US |
dc.format.extent | 648345 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 1993 Diabetes UK | en_US |
dc.subject.other | Diabetic Neuropathy | en_US |
dc.subject.other | Axo-glial Dysjunction | en_US |
dc.subject.other | Axonal Atrophy Sural Nerve Conduction Velocity | en_US |
dc.subject.other | Aldose Reductase Inhibition | en_US |
dc.title | Overt Diabetic Neuropathy: Repair of Axo-glial Dysjunction and Axonal Atrophy by Aldose Reductase Inhibition and its Correlation to Improvement in Nerve Conduction Velocity | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Michigan Diabetes Research and Training Center and Departments of Pathology and Internal Medicine, University of Michigan, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationother | Neuropathology Research Laboratories, Department of Pathology, University of Manitoba, Winnipeg, Canada | en_US |
dc.contributor.affiliationother | Department of Medicine, University of Toronto, Toronto, Ontario, Canada | en_US |
dc.identifier.pmid | 8458187 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/74171/1/j.1464-5491.1993.tb00027.x.pdf | |
dc.identifier.doi | 10.1111/j.1464-5491.1993.tb00027.x | en_US |
dc.identifier.source | Diabetic Medicine | en_US |
dc.identifier.citedreference | Greene DA, Lattimer SA, Sima AAF. Sorbitol, phosphoinositides, and sodium-potassium-ATP-ase in the pathogenesis of diabetic complications. N Engl J Med 1987; 316: 599 – 606. | en_US |
dc.identifier.citedreference | Winegrad AI. Does a common mechanism induce the diverse complications of diabetes? Diabetes 1987; 36: 396 – 406. | en_US |
dc.identifier.citedreference | Greene DA, Lattimer-Greene SA, Sima AAF. Pathogenesis of diabetic neuropathy: role of altered phosphoinositide metabolism. Crit Rev Neurobiol 1989; 5: 143 – 219. | en_US |
dc.identifier.citedreference | Greene DA, Sima AAF, Albers JW, Pfeifer M.. Diabetic Neuropathy In: Rifkin H., Porte D. Jr., eds, Ellenberg and Rifkin Diabetes Mellitus. New York: Elsevier, 1989. 710 – 755. | en_US |
dc.identifier.citedreference | Dyck PJ, Karnes JL, O'Brien P., Okazaki H., Lais A., Engelstad J.. The spatial distribution of fiber loss in diabetic polyneuropathy suggests ischemia. Ann Neurol 1986; 19: 440 – 444. | en_US |
dc.identifier.citedreference | Sima AAF, Nathaniel V., Prashar A., Bril, V. Greene, DA. Endoneurial microvessels in human diabetic neuropathy: Endothelial cell dysjunction and lack of treatment effect by aldose reductase inhibitor. Diabetes 1991; 40: 1090 – 1099. | en_US |
dc.identifier.citedreference | Pirart J.. Diabetes mellitus and its degenerative complications: a prospective study of 4,400 patients observed between 1947 and 1973. Diabetes Care 1978; 1: 168 – 188. | en_US |
dc.identifier.citedreference | 8 The DCCT Research Group. Factors in the development of diabetic neuropathy: baseline analysis of neuropathy in feasibility phase of diabetes control and complications trial (DCCT). Diabetes 1988; 37: 476 – 481. | en_US |
dc.identifier.citedreference | Moser RE, Steenkiste AR, Dorman JS, Nielson VK, Bass EB, Manjoo Q., et al. Epidemiological correlates of diabetic neuropathy. Report from Pittsburgh epidemiology of diabetes complications study. Diabetes 1989; 38: 1456 – 1461. | en_US |
dc.identifier.citedreference | Sima AAF. Can the BB-rat help to unravel diabetic neuropathy? Neuropath Appl Neurobiol 1985; 11: 253 – 264. | en_US |
dc.identifier.citedreference | Sima AAF, Brismar T., Yagihashi S.. Neuropathies encountered in the spontaneously diabetic BB-Wistar rat. In: PJ Dyck, PK Thomas, AK Asbury, AI Winegrad and D. Porte Jr., eds. Diabetic Neuropathy. Philadelphia: WB Saunders, 1987. 253 – 259. | en_US |
dc.identifier.citedreference | Greene DA, Yagihashi S., Lattimer SA, Sima AAF. Na+K+-ATP-ase, conduction and myo-inositol in the insulin deficient BB-rat. Am J Phys 1984; 247: E534 – E539. | en_US |
dc.identifier.citedreference | Sima AAF, Brismar T.. Reversible diabetic nerve dysfunction: structural correlates to electrophysiological abnormalities. Ann Neurol 1985; 18: 21 – 29. | en_US |
dc.identifier.citedreference | Brismar T., Sima AAF, Greene DA. Reversible and irreversible nodal dysfunction in diabetic neuropathy. Ann Neurol 1987; 21: 504 – 507. | en_US |
dc.identifier.citedreference | Sima AAF, Lattimer SA, Yagihashi S., Greene DA. Axoglial dysjunction. A novel structural lesion that accounts for poorly reversible slowing of nerve conduction in the spontaneously diabetic Bio-breeding rat. J Clin Invest 1986; 77: 474 – 484. | en_US |
dc.identifier.citedreference | Kinoshita JH. Cataracts in galactosemia. Invest Ophthalmol 1965; 4: 786 – 799. | en_US |
dc.identifier.citedreference | Gabbay KH, Merola LO, Field RA. Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes. Science 1966; 151: 209 – 210. | en_US |
dc.identifier.citedreference | Dvornik D., Porte D. Jr. Aldose reductase inhibition: an approach to the prevention of diabetic complications. New York: McGraw-Hill, 1987. | en_US |
dc.identifier.citedreference | Greene DA, Chakrabarti S., Lattimer SA, Sima AAF. Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibres in the insulin-deficient spontaneously diabetic Bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor and myo-inositol. J Clin Invest 1987; 79: 1479 – 1485. | en_US |
dc.identifier.citedreference | Greene DA, Lattimer SA. Action of sorbinil in diabetic peripheral nerve: relationship of polyol (sorbitol) pathway inhibition to a myo-inositol mediated defect in sodium-potassium ATPase activity. Diabetes 1984; 33: 712 – 716. | en_US |
dc.identifier.citedreference | Sima AAF, Bril V., Nathaniel V., McEwen TAJ, Brown MB, Lattimer SA, et al. Regeneration and repair of myelinated fibers in sural nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil. N Engl J Med 1988; 319: 548 – 555. | en_US |
dc.identifier.citedreference | Sima AAF, Prashar A., Zhang W-X, Chakrabarti S., Greene DA. The preventive effect of long term aldose reductase inhibition (Ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic BB-rat. J Clin Invest 1990; 85: 1410 – 1420. | en_US |
dc.identifier.citedreference | Sima AAF, Cherian PV, Carson C., Kamijo M., Chakrabarti S.. Diabetic optic neuropathy and its prevention in the BB/W-rat with an aldose reductase inhibitor. Diabetes 1992; 41: ( suppl 1 ): 139A. | en_US |
dc.identifier.citedreference | Sima AAF, Nathaniel V., Bril V., McEwen TAJ, Greene DA. Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes. and demonstration of axo-glial dysjunction in human diabetic neuropathy. J Clin Invest 1988; 81: 349 – 364. | en_US |
dc.identifier.citedreference | 25 National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979; 28: 1039 – 1057. | en_US |
dc.identifier.citedreference | Sima AAF, Brown MB, Prashar A., Chakrabarti C., Laudadio C., Greene DA. The reproducibility and sensitivity of sural nerve morphometry in the assessment of diabetic peripheral polyneuropathy. Diabetologia 1992; 35: 560 – 569. | en_US |
dc.identifier.citedreference | Brismar T., Sima AAF. Changes in nodal function in nerve fibres of the spontaneously diabetic BB-Wistar rat. Potential clamp analysis. Acta Physiol Scand 1981; 1134: 499 – 506. | en_US |
dc.identifier.citedreference | Bischoff A.. Diabetische Neuropathie. Dtsch Med Wochenschr 1968; 93: 237 – 241. | en_US |
dc.identifier.citedreference | Yagihashi S.. Matsumaja M. Ultrastructural pathology of peripheral nerves in patients with diabetic neuropathy. Tohoku J Exp Med 1979; 129: 357 – 366. | en_US |
dc.identifier.citedreference | Dyck PJ, Lais A., Karnes JL, O'Brien P., Rizza R.. Fiber loss is primary and multifocal in sural nerves in diabetic polyneuropathy. Ann Neurol 1986; 19: 425 – 439. | en_US |
dc.identifier.citedreference | Behse F., Buchtal F., Carlsen F.. Nerve biopsy and conduction studies and diabetic neuropathy. J Neurol Neurosurg Psychiatry 1977; 40: 1072 – 1082. | en_US |
dc.identifier.citedreference | Medori R., Autilio-Gambetti L., Jenich H., Gambetti P.. Changes in axonal size and slow axonal transport are related in experimental diabetic neuropathy. Neurology 1988; 38: 597 – 601. | en_US |
dc.identifier.citedreference | Mayer JH, Tomlinson DR. Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin diabetic rats. Diabetologia 1983; 25: 433 – 438. | en_US |
dc.identifier.citedreference | Thomas PK, Wright DW, Tzebelikas E.. Amino acid uptake by dorsal root ganglia from streptozotocin-diabetic rats. J Neurol Neurosurg Psychiatry 1984; 47: 912 – 916. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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