Efficient and quantitative incorporation of diaminopimelic acid into the peptidoglycan of Salmonella typhimurium
dc.contributor.author | Cooper, Stephen | en_US |
dc.contributor.author | Metzger, Nicholas | en_US |
dc.date.accessioned | 2010-06-01T21:08:00Z | |
dc.date.available | 2010-06-01T21:08:00Z | |
dc.date.issued | 1986-09 | en_US |
dc.identifier.citation | Cooper, Stephen; Metzger, Nicholas (1986). "Efficient and quantitative incorporation of diaminopimelic acid into the peptidoglycan of Salmonella typhimurium ." FEMS Microbiology Letters 36(2-3): 191-194. <http://hdl.handle.net/2027.42/74216> | en_US |
dc.identifier.issn | 0378-1097 | en_US |
dc.identifier.issn | 1574-6968 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/74216 | |
dc.description.abstract | Diaminopimelic acid is incorporated into the peptidoglycan of Salmonella typhimurium in an efficient and quantitative manner. The amount of DAP incorporated is similar to the number of molecules estimated to exist in the Salmonella cell wall. In contrast, strains of E. coli , including those most used for studies of cell wall synthesis, are much less efficient in the incorporation of diaminopimelic acid. The lysine-requiring strains of E. coli appear to excrete diaminopimelic acid related material during growth and this accounts, in part, for the inefficient incorporation of radioactive diaminopimelic acid into Escherichia strains. In addition, the Escherichia strains are much less permeable to DAP than Salmonella strains. Cysteine and cystine inhibit the incorporation of DAP into the cell and this result suggests that Salmonella uses the cystine uptake system to allow DAP into the cell. | en_US |
dc.format.extent | 297413 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 1986 Federation of European Microbiological Societies | en_US |
dc.subject.other | Salmonella Typhimurium | en_US |
dc.subject.other | Peptidoglycan | en_US |
dc.subject.other | Diaminopimetic Acid Incorporation | en_US |
dc.title | Efficient and quantitative incorporation of diaminopimelic acid into the peptidoglycan of Salmonella typhimurium | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Microbiology and Immunology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109-0620, U.S.A. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/74216/1/j.1574-6968.1986.tb01694.x.pdf | |
dc.identifier.doi | 10.1111/j.1574-6968.1986.tb01694.x | en_US |
dc.identifier.source | FEMS Microbiology Letters | en_US |
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dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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