Accuracy of the Fetal Echocardiogram in Double-outlet Right Ventricle

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dc.contributor.author Gelehrter, Sarah en_US
dc.contributor.author Owens, Sonal T. en_US
dc.contributor.author Russell, Mark W. en_US
dc.contributor.author van der Velde, Mary E. en_US
dc.contributor.author Gomez-Fifer, Carlen en_US
dc.date.accessioned 2010-06-01T21:10:03Z
dc.date.available 2010-06-01T21:10:03Z
dc.date.issued 2007-01 en_US
dc.identifier.citation Gelehrter, Sarah; Owens, Sonal T.; Russell, Mark W.; van der Velde, Mary E.; Gomez-Fifer, Carlen (2007). "Accuracy of the Fetal Echocardiogram in Double-outlet Right Ventricle." Congenital Heart Disease 2(1): 32-37. <http://hdl.handle.net/2027.42/74249> en_US
dc.identifier.issn 1747-079X en_US
dc.identifier.issn 1747-0803 en_US
dc.identifier.uri http://hdl.handle.net/2027.42/74249
dc.identifier.uri http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18377514&dopt=citation en_US
dc.description.abstract Objective.  Double-outlet right ventricle (DORV) is a complex congenital heart defect with heterogeneous anatomy. Patients require a variety of surgical interventions, and the long-term prognosis is variable. Therefore, accurate prenatal diagnosis is important in providing parents with appropriate counseling. Design.  Medical records were reviewed in patients with a diagnosis of DORV who had fetal echocardiography at our institution from 1998 to 2004. Pre- and postnatal diagnoses were compared, anticipated surgical procedure was compared with surgery performed, and neonatal outcome was assessed. Results.  The study group consisted of 49 fetal patients with 6 in utero deaths (including 4 terminations), 2 patients lost to follow-up, and 41 live births. Postnatal echocardiograms or autopsy results were available on 42 patients. The overall accuracy of fetal echocardiography in making a correct diagnosis of DORV was 76%. Accurate prenatal prediction of the type of cardiac surgery that would be performed was made in 91% of patients who had surgery. Among live births, survival to hospital discharge was 76%. Survival was 50% in patients with extracardiac or chromosomal anomalies, compared with 92% in infants without additional anomalies. Conclusion.  In most cases, careful evaluation by fetal echocardiography can determine essential anatomic details in fetuses with DORV with enough accuracy to allow for accurate counseling regarding the type of surgery needed. Survival is better than previously reported but is poor in patients with extracardiac or chromosomal abnormalities. en_US
dc.format.extent 200829 bytes
dc.format.extent 3109 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.publisher Blackwell Publishing Inc en_US
dc.rights © 2007, the Authors; Journal compilation © 2007, Blackwell Publishing, Inc. en_US
dc.subject.other Fetal Echocardiography en_US
dc.subject.other Double-outlet Right Ventricle en_US
dc.subject.other Congenital Heart Disease en_US
dc.title Accuracy of the Fetal Echocardiogram in Double-outlet Right Ventricle en_US
dc.type Article en_US
dc.subject.hlbsecondlevel Internal Medicine and Specialties en_US
dc.subject.hlbtoplevel Health Sciences en_US
dc.description.peerreviewed Peer Reviewed en_US
dc.identifier.pmid 18377514 en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/74249/1/j.1747-0803.2007.00069.x.pdf
dc.identifier.doi 10.1111/j.1747-0803.2007.00069.x en_US
dc.identifier.source Congenital Heart Disease en_US
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dc.owningcollname Interdisciplinary and Peer-Reviewed
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