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Type II secretion: from structure to function
dc.contributor.authorJohnson, Tanya L.en_US
dc.contributor.authorAbendroth, Janen_US
dc.contributor.authorHol, Wim G. J.en_US
dc.contributor.authorSandkvist, Mariaen_US
dc.date.accessioned2010-06-01T21:31:10Z
dc.date.available2010-06-01T21:31:10Z
dc.date.issued2006-02en_US
dc.identifier.citationJohnson, Tanya L.; Abendroth, Jan; Hol, Wim G . J.; Sandkvist, Maria (2006). "Type II secretion: from structure to function." FEMS Microbiology Letters 255(2): 175-186. <http://hdl.handle.net/2027.42/74575>en_US
dc.identifier.issn0378-1097en_US
dc.identifier.issn1574-6968en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74575
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16448494&dopt=citationen_US
dc.description.abstractGram-negative bacteria use the type II secretion system to transport a large number of secreted proteins from the periplasmic space into the extracellular environment. Many of the secreted proteins are major virulence factors in plants and animals. The components of the type II secretion system are located in both the inner and outer membranes where they assemble into a multi-protein, cell-envelope spanning, complex. This review discusses recent progress, particularly newly published structures obtained by X-ray crystallography and electron microscopy that have increased our understanding of how the type II secretion apparatus functions and the role that individual proteins play in this complex system.en_US
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dc.publisherBlackwell Science Ltden_US
dc.rights© 2006 Federation of European Microbiological Societiesen_US
dc.subject.otherType II Secretionen_US
dc.subject.otherElectron Microscopyen_US
dc.subject.otherX-ray Structuresen_US
dc.titleType II secretion: from structure to functionen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMicrobiology and Immunologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA anden_US
dc.contributor.affiliationotherDepartment of Biochemistry, Biomolecular Structure Center, School of Medicine, University of Washington, Seattle, WA, USAen_US
dc.identifier.pmid16448494en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74575/1/j.1574-6968.2006.00102.x.pdf
dc.identifier.doi10.1111/j.1574-6968.2006.00102.xen_US
dc.identifier.sourceFEMS Microbiology Lettersen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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