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Catecholamine Levels in Tricyclic Antidepressant Self-Poisoning
dc.contributor.authorSchwarz, R.en_US
dc.contributor.authorEsler, Murray D.en_US
dc.date.accessioned2010-06-01T21:33:13Z
dc.date.available2010-06-01T21:33:13Z
dc.date.issued1974-10en_US
dc.identifier.citationSchwarz, R.; Esler, M. (1974). "Catecholamine Levels in Tricyclic Antidepressant Self-Poisoning." Internal Medicine Journal 4(5): 479-484. <http://hdl.handle.net/2027.42/74606>en_US
dc.identifier.issn1444-0903en_US
dc.identifier.issn1445-5994en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74606
dc.description.abstractIn a consecutive series of 20, patients with tricyclic antidepressant self-poisoning, urinary catecholamine excretion was measured, and the catecholamine level compared with that in ten patients having taken an overdose of other drugs. In both patient groups the electrocardiograph was monitored continuously for a minimum of 48 hours to detect cardiac arrhythmias. Urinary nor-adrenaline excretion was elevated during the first 24 hours after tricyclic anti-depressant self-poisoning, to a level 2–3 times that found in the other overdose group, but was normal by the third day. Cardiac tachyarrhythmias developed in four of the patients with antidepressant overdosage. The findings support the concept that sympathetic nervous system overactivity underlies the cardiac tachyarrhythmias which commonly accompany self-poisoning with this class of drugs.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1974 Published on behalf of the Adult Medicine Division of the Royal Australasian College of Physiciansen_US
dc.titleCatecholamine Levels in Tricyclic Antidepressant Self-Poisoningen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationum*Registrar in Psychiatry; Currently Resident in Psychiatry, Ypsilanti State Hospital Ypsilanti, Michigan U.S.A.en_US
dc.contributor.affiliationum†Research Associate; Currently Fellow in Hypertension, Department of Internal Medicine, University Hospital, Ann Arbor, Michigan U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74606/1/j.1445-5994.1974.tb03221.x.pdf
dc.identifier.doi10.1111/j.1445-5994.1974.tb03221.xen_US
dc.identifier.sourceInternal Medicine Journalen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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