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Potential Role of Protease Nexin-2/Amyloid Β-Protein Precursor as a Cerebral Anticoagulant a

dc.contributor.authorNostrand, William E.en_US
dc.contributor.authorSchmaier, Alvin H.en_US
dc.contributor.authorWagner, Steven L.en_US
dc.date.accessioned2010-06-01T21:40:35Z
dc.date.available2010-06-01T21:40:35Z
dc.date.issued1992-12en_US
dc.identifier.citationNOSTRAND, WILLIAM E.; SCHMAIER, ALVIN H.; WAGNER, STEVEN L. (1992). "Potential Role of Protease Nexin-2/Amyloid Β-Protein Precursor as a Cerebral Anticoagulant a ." Annals of the New York Academy of Sciences 674(1 Proteases and Protease Inhibitors in Alzheimer's Disease Pathogenesis ): 243-252. <http://hdl.handle.net/2027.42/74723>en_US
dc.identifier.issn0077-8923en_US
dc.identifier.issn1749-6632en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74723
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1288367&dopt=citationen_US
dc.format.extent619593 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights1992 The New York Academy of Sciencesen_US
dc.titlePotential Role of Protease Nexin-2/Amyloid Β-Protein Precursor as a Cerebral Anticoagulant aen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelScience (General)en_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Internal Medicine Division of Hematology/Oncology University of Michigan Ann Arbor, Michigan 48109-0724en_US
dc.contributor.affiliationotherDepartment of Microbiology and Molecular Genetics University of California Irvine, California 92717en_US
dc.contributor.affiliationotherSalk Institute Biotechnology/Industrial Associates 505 Coast Boulevard South La Jolla, California 92037en_US
dc.identifier.pmid1288367en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74723/1/j.1749-6632.1992.tb27493.x.pdf
dc.identifier.doi10.1111/j.1749-6632.1992.tb27493.xen_US
dc.identifier.sourceAnnals of the New York Academy of Sciencesen_US
dc.identifier.citedreferenceGlenner, G. G. & C. W. Wong. 1984. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophy. Res. Commun. 120: 885 – 890.en_US
dc.identifier.citedreferenceGlenner, G. G. & C. W. Wong. 1984. Alzheimer's disease and Down's syndrome sharing of a unique cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 122: 1131 – 1135.en_US
dc.identifier.citedreferenceMasters, C. L., G. Multhaup, G. Simms, J. Pottgiesser, R. N. Martins & K. Beyreuther, 1985. Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J. 4: 2757 – 2763.en_US
dc.identifier.citedreferenceMasters, C. L., G. Simms, N. A. Weinmann, G. Multhaup, B. L. McDonald & K. Beyreuther, 1985. Amyloid plaque core protein in Alzheimer's disease and Down syndrome. Proc. Natl. Acad. Sci. USA 82: 4245 – 4249.en_US
dc.identifier.citedreferenceMasters, C. L. & K. Beyreuther, 1988. In Aging of the Brain Vol. 32: 183 – 204. Raven Press. New York.en_US
dc.identifier.citedreferencevan Duinen, S. G., E. M. Castano, F. Prelli, G. T. A. M. Bots, W. Luyendijk & B. Frangione. 1987. Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease. Proc. Natl. Acad. Sci. USA 84: 5991 – 5994.en_US
dc.identifier.citedreferenceKang, J., H.-G. Lemaire, A. Unterbeck, J. M. Salbaum, C. L. Masters, K. H. Grzeschik, G. Multhaup, K. Beyreuther & B. Muller-Hill, 1987. The precursor of Alzheimer disease amyloid A4 protein resembles a cell surface receptor. Nature 325: 733 – 736.en_US
dc.identifier.citedreferenceGoldgaber, D., M. I. Lerman, O. W. McBride, U. Saffiotti & D. C. Gajdusek, 1987. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235: 877 – 880.en_US
dc.identifier.citedreferenceTanzi, R. E., J. F. Gusella, P. C. Watkins, G. A. P. Bruns, P. St. George-Hyslop, M. L. Van Keuren, D. Patterson, S. Pagan, D. M. Kurnit & R. L. Neve, 1987. Amyloid Β protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer's locus. Science 235: 880 – 884.en_US
dc.identifier.citedreferenceRobakis, N. K., N. Ramakrishna, G. Wolfe & H. M. Wisniewski, 1987. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc. Natl. Acad. Sci. USA 84: 4190 – 4194.en_US
dc.identifier.citedreferencePonte, P., P. Gonzalez-DeWhitt, J. Schilling, J. Miller, D. Hsu, B. Greenberg, K. Davis, W. Wallace, I. Lieberburg, F. Fuller & B. Cordell, 1988. A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors. Nature 331: 525 – 527.en_US
dc.identifier.citedreferenceTanzi, R. E., A. I. McClatchey, E. D. Lamperti, L. Villa-Komaroff, J. F. Gusella & R. L. Neve, 1988. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331: 528 – 530.en_US
dc.identifier.citedreferenceKitaguchi, N., Y. Takahashi, Y. Tokushima, S. Shiojiri & H. Pro, 1988. Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331: 530 – 532.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., S. L. Wagner, M. Suzuki, B. H. Choi, J. S. Farrow, J. W. Geddes, C. W. Cotman & D. D. Cunningham, 1989. Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid Β-protein precursor. Nature 341: 546 – 549.en_US
dc.identifier.citedreferenceOltersdorf, T., L. C. Fritz, D. B. Schenk, I. Lieberburg, K. L. Johnson-Wood, E. C. Beattie, P. J. Ward, R. W. Blacher, H. F. Dovey & S. Sinha, 1989. The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. Nature 341: 144 – 147.en_US
dc.identifier.citedreferenceSisodia, S. S., E. H. Koo, K. Beyreuther, A. Unterbeck & D. L. Price, 1990. Evidence that Β-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248: 492 – 495.en_US
dc.identifier.citedreferenceEsch, F. S., P. S. Keim, E. C. Beattie, R. W. Blacher, A. R. Culwell, T. Oltersdorf, D. McClure & P. J. Ward, 1990. Cleavage of amyloid to peptide during constitutive processing of its precursor. Science 248: 1122 – 1124.en_US
dc.identifier.citedreferenceWang, R., J. F. Meschia, R. J. Cotter & S. S. Sisodia, 1991. Secretion of the Β /A4 amyloid precursor protein. J. Biol. Chem. 266: 16960 – 16964.en_US
dc.identifier.citedreferenceGolde, T. E., S. Estus, M. Usiak, L. H. Younkin & S. G. Younkin, 1990. Expression of Β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron 4: 253 – 267.en_US
dc.identifier.citedreferencePalmert, M. R., M. B. Podlisny, D. S. Witker, T. Oltersdorf, L. H. Younkin, D. J. Selkoe & S. G. Younkin, 1988. Antisera to an amino terminal peptide detect the amyloid protein precursor of Alzheimer's disease and recognize senile plaques. Biochem. Biophys. Res. Commun. 156: 432 – 437.en_US
dc.identifier.citedreferencePalmert, M. R., M. B. Podlisny, D. S. Witker, T. Oltersdorf, L. H. Younkin, D. J. Selkoe & S. G. Younkin, 1989. The Β-amyloid protein precursor of Alzheimer's disease has soluble derivatives found in human brain and cerebrospinal fluid. Proc. Natl. Acad. Sci. USA 86: 6338 – 6342.en_US
dc.identifier.citedreferenceWeidemann, A., G. Konig, D. Bunke, P. Fischer, J. M. Salbaum, C. L. Masters & K. Beyreuther, 1989. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57: 115 – 126.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., J. S. Farrow, S. L. Wagner, R. Bhasin, D. Goldgaber, C. W. Cotman & D. D. Cunningham, 1991. The predominant form of the amyloid Β-protein precursor in human brain is protease nexin-2. Proc. Natl. Acad. Sci. USA 88: 10302 – 10306.en_US
dc.identifier.citedreferenceKnauer, D. J. & D. D. Cunningham, 1982. Epidermal growth factor carrier protein binds to cells via a complex with released carrier protein nexin. Proc. Natl. Acad. Sci. USA 79: 2310 – 2314.en_US
dc.identifier.citedreferenceKnauer, D. J., J. A. Thompson & D. D. Cunningham, 1983. Protease nexins: cell secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases. J. Cell. Physiol. 117: 385 – 396.en_US
dc.identifier.citedreferenceVan Nostrand, W. E. & D. D. Cunningham. 1987. Purification of protease nexin II from human fibroblasts. J. Biol. Chem. 262: 8508 – 8514.en_US
dc.identifier.citedreferenceHenriksson, T., R. M. Barbour, S. Braa, P. Ward, L. C. Fritz, K. Johnson-Wood, H. D. Chung, W. Burke, K. J. Reinikainen, P. Reikkinen & D. B. Schenk. 1991. Analysis and quantitation of the Β -amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients with a monoclonal antibody-based immunoassay. J. Neurochem. 56: 1037 – 1042.en_US
dc.identifier.citedreferenceArai, H., V. M.-Y. Lee, M. L. Messinger, B. D. Greenberg, D. E. Lowery & J. Q. Trojanowsm. 1991. Expression patterns of Β -amyloid precursor ( Β -APP) in neural and nonneural tissues from Alzheimer's disease and control subjects. Ann. Neurol. 30: 686 – 693.en_US
dc.identifier.citedreferenceGoldgaber, D., H. W. Harris, T. Hla, T. Maciag, J. Donnelly, S. Jacobsen, M. P. Vitek & D. C. Gajdusek. 1989. Interleukin 1 regulates synthesis of amyloid Β -protein precursor mRNA in human endothelial cells. Proc. Natl. Acad. Sci. USA 86: 7606 – 7610.en_US
dc.identifier.citedreferenceGriffin, W. S. T., L. C. Stanley, C. Ling, L. White, V. MacLeod, L. J. Perrot, C. L. White & C. Araoz. 1989. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc. Natl. Acad. Sci. USA 86: 7611 – 7615.en_US
dc.identifier.citedreferenceTagliavini, F., J. Ghiso, W. F. Timmers, G. Giaccone, O. Bugiani & B. Frangione. 1990. Coexistence of Alzheimer's amyloid precursor protein and amyloid protein in cerebral vessel walls. Lab. Invest. 62: 761 – 767.en_US
dc.identifier.citedreferencePodlisny, M. B., A. L. Mammen, M. G. Schlossmacher, M. R. Palmert, S. G. Younkin & D. J. Selkoe. 1990. Detection of soluble forms of the Β-amyloid precursor protein in human plasma. Biochem. Biophys. Res. Commun. 167: 1094 – 1101.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., A. H. Schmaier, J. S. Farrow & D. D. Cunningham. 1990. Protease nexin-II (amyloid Β-protein precursor): a platelet a granule protein. Science 248: 745 – 748.en_US
dc.identifier.citedreferenceSmith, R. P., D. A. Higuchi & G. J. Broze, Jr. 1990. Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein. Science 248: 1126 – 1128.en_US
dc.identifier.citedreferenceBush, A. I., R. N. Martins, B. Rumble, R. Moir, S. Fuller, E. Milward, J. Currie, D. Ames, A. Weidemann, P. Fischer, G. Multhaup, K. Beyreuther & C. L. Masters. 1990. The amyloid precursor protein of Alzheimer's disease is released by human platelets. J. Biol. Chem. 265: 15977 – 15983.en_US
dc.identifier.citedreferenceGardella, J. E., J. Ghiso, G. A. Gorgone, D. Marratta, A. P. Kaplan, B. Frangione & P. D. Gorevic. 1990. Intact Alzheimer amyloid precursor protein (APP) is present in platelet membranes and is encoded by platelet mRNA. Biochem. Biophys. Res. Commun. 173: 1292 – 1298.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., A. H. Schmaier, J. S. Farrow, D. B. Cines & D. D. Cunningham. 1991. Protease nexin-2 [amyloid Β-protein precursor] is a platelet-specific protein in blood. Biochem. Biophys. Res. Commun. 175: 15 – 21.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., S. L. Wagner, J. S. Farrow & D. D. Cunningham. 1990. Immunopurification and protease inhibitory properties of protease nexin-2/amyloid Β-protein precursor. J. Biol. Chem. 265: 9591 – 9594.en_US
dc.identifier.citedreferenceSinha, S., H. F. Dovey, P. Seubert, P. J. Ward, R. W. Blacher, M. Blaber, R. A. Bradshaw, M. Arici, W. C. Mobley & I. Lieberburg. 1990. The protease inhibitory properties of the Alzheimer's Β-amyloid precursor protein. J. Biol. Chem. 265: 8983 – 8985.en_US
dc.identifier.citedreferenceJackson, C. M. & Y. Nemerson. 1980. Blood coagulation. Annu. Rev. Biochem. 49: 765 – 811.en_US
dc.identifier.citedreferenceVan Nostrand, W. E., A. H. Schmaier, J. S. Farrow & D. D. Cunningham. 1991. Platelet protease nexin-2/amyloid Β-protein precursor; possible pathologic and physiologic functions. Ann. N.Y. Acad. Sci. 640: 140 – 144.en_US
dc.identifier.citedreferenceNaito, K. & K. Fujikawa. 1991. Activation of human blood coagulation factor XI independent of factor XII. J. Biol. Chem. 266: 7353 – 7358.en_US
dc.identifier.citedreferenceGailani, D. & G. J. Broze. 1991. Factor XI activation in a revised model of blood coagulation. Science 253: 909 – 912.en_US
dc.identifier.citedreferenceEsmon, C. T. 1987. The regulation of natural anticoagulant pathways. Science 235: 1348 – 1352.en_US
dc.identifier.citedreferenceMaruyama, I., C. E. Bell & P. W. Majerus. 1985. Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta. J. Cell. Biol. 101: 363 – 371.en_US
dc.identifier.citedreferenceWagner, S. L., J. W. Geddes, C. W. Cotman, A. L. Lau, D. Gurwitz, P. J. Isackson & D. D. Cunningham. 1989. Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proc. Natl. Acad. Sci. USA 86: 8284 – 8288.en_US
dc.identifier.citedreferenceChoi, B. H., M. Suzuki, T. Kim, S. L. Wagner & D. D. Cunningham. 1990. Protease nexin-1: localization in the human brain suggests a protective role against extravasated serine proteases. Am. J. Pathol. 137: 741 – 747.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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