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Adrenalectomy-Produced Facilitation of Pavlovian Conditioned Cardiodecelerations in Immobilized Rats

dc.contributor.authorWilson, J. Rogeren_US
dc.contributor.authorSimpson, C. Wayneen_US
dc.contributor.authorDiCara, Leo V.en_US
dc.contributor.authorCarroll, Bernard J.en_US
dc.date.accessioned2010-06-01T22:02:33Z
dc.date.available2010-06-01T22:02:33Z
dc.date.issued1977-03en_US
dc.identifier.citationWilson, J. Roger; Simpson, C. Wayne; DiCara, Leo V.; Carroll, Bernard J. (1977). "Adrenalectomy-Produced Facilitation of Pavlovian Conditioned Cardiodecelerations in Immobilized Rats." Psychophysiology 14(2): 172-181. <http://hdl.handle.net/2027.42/75069>en_US
dc.identifier.issn0048-5772en_US
dc.identifier.issn1469-8986en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75069
dc.description.abstractPrevious evidence has suggested that both hormonal and behavioral aspects of adrenal stress activation may contribute to heart rate (HR) conditioning during physical/pharmacological immobilization. Accordingly, four studies were conducted to determine if bilateral adrenalectomy facilitates stimulus-control over Pavlovian conditioned cardiodecelerations in rats immobilized either through physical restraint or neuromuscular paralysis. Plasma corticosterone assays were used as an index of the effectiveness of adrenal removal. The results showed that adrenalectomy facilitated both simple and discriminated Pavlovian conditioned cardiodecelerations in rats paralyzed with d-tubocurarine chloride (dTC) without significantly altering the characteristics of EMG recovery from paralysis. Similarly, adrenalectomy facilitated simple Pavlovian HR conditioning in physically restrained rats. The results suggest that adrenal activation may disrupt the parasympathetically-mediated Pavlovian conditioned cardiodeceleration in the physically-and dTC-immobilized rat. However, the specific nature of neuroendocrine mechanisms underlying cardiovascular conditioning during immobilization remains problematical.en_US
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dc.format.extent3109 bytes
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dc.publisherBlackwell Publishing Ltden_US
dc.rights1977 The Society for Psychophysiological Research, Inc.en_US
dc.subject.otherHeart Rateen_US
dc.subject.otherConditioningen_US
dc.subject.otherAdrenal Stressen_US
dc.subject.otherRatsen_US
dc.titleAdrenalectomy-Produced Facilitation of Pavlovian Conditioned Cardiodecelerations in Immobilized Ratsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPhysiologyen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arboren_US
dc.identifier.pmid847069en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75069/1/j.1469-8986.1977.tb03371.x.pdf
dc.identifier.doi10.1111/j.1469-8986.1977.tb03371.xen_US
dc.identifier.sourcePsychophysiologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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