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On the use of metaphor to understand, explain, or rationalize redundant genes in yeast
dc.contributor.authorCooper, Stephenen_US
dc.date.accessioned2010-06-01T22:04:47Z
dc.date.available2010-06-01T22:04:47Z
dc.date.issued2008-05en_US
dc.identifier.citationCooper, Stephen (2008). "On the use of metaphor to understand, explain, or rationalize redundant genes in yeast." FEMS Yeast Research 8(3): 345-348. <http://hdl.handle.net/2027.42/75104>en_US
dc.identifier.issn1567-1356en_US
dc.identifier.issn1567-1364en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75104
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18294197&dopt=citationen_US
dc.description.abstractThe proposal that yeast, and cells in general, contains redundant genes that enable cells to survive mutational change has been supported by experiments and a strong metaphor. The redundant gene proposal is analyzed, and it is noted that there are many problems with the redundant gene model. An alternative metaphor is suggested to explain the genetic composition of a yeast culture.en_US
dc.format.extent59233 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights© 2008 Federation of European Microbiological Societies/Blackwell Publishing Ltden_US
dc.subject.otherRedundant Genesen_US
dc.subject.otherLethal Genesen_US
dc.subject.otherGenetic Analysisen_US
dc.subject.otherCheckpointsen_US
dc.titleOn the use of metaphor to understand, explain, or rationalize redundant genes in yeasten_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMicrobiology and Immunologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USAen_US
dc.identifier.pmid18294197en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75104/1/j.1567-1364.2008.00353.x.pdf
dc.identifier.doi10.1111/j.1567-1364.2008.00353.xen_US
dc.identifier.sourceFEMS Yeast Researchen_US
dc.identifier.citedreferenceHolzman D ( 2006 ) In Yeast, Genetic Redundancies Help to Ensure Genomic Integrity. Microbe 1: 262 – 263.en_US
dc.identifier.citedreferencePan X, Ye P, Yuan DS, Wang X, Bader JS & Boeke JD ( 2006 ) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124: 1069 – 1081.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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