The effects of periodontal therapy on serum antibody (IgG) levels to plaque microorganisms *
dc.contributor.author | Aukhil, Ikramuddin | en_US |
dc.contributor.author | Lopatinct, Dennis E. | en_US |
dc.contributor.author | Syed, Salam A. | en_US |
dc.contributor.author | Morrison, Edith C. | en_US |
dc.contributor.author | Kowatsk, Charles J. | en_US |
dc.date.accessioned | 2010-06-01T22:05:10Z | |
dc.date.available | 2010-06-01T22:05:10Z | |
dc.date.issued | 1988-10 | en_US |
dc.identifier.citation | Aukhil, Ikramuddin; Lopatinct, Dennis E.; Syed, Salam A.; Morrison, Edith C.; Kowatsk, Charles J. (1988). "The effects of periodontal therapy on serum antibody (IgG) levels to plaque microorganisms * ." Journal of Clinical Periodontology 15(9): 544-550. <http://hdl.handle.net/2027.42/75110> | en_US |
dc.identifier.issn | 0303-6979 | en_US |
dc.identifier.issn | 1600-051X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/75110 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3198782&dopt=citation | en_US |
dc.description.abstract | The influence of periodontal therapy on serum antibody titers to selected periodontal disease-associated microorganisms was assessed in 23 patients having chronic inflammatory periodontal disease (CIPD), The immunoglobulin G (IgG) titers were dÉtÉrmined by the micro ELISA technique in serum samples obtained prior to treatment; following a hygienic phase which included scaling, root planing, and oral hygiene instruction; following surgical treatment; and one year and two years following hygienic phase (maintenance phase). Considerable individual variability existed in the magnitude of immune response to specific bacterial preparations. Significant reductions in the mean antibody titers were seen to A. viscosus. S. sanguis. F. nucleatum, S, spuligena, B. gingivalis. B. interme-dius. B. melaninogeniem, T. vincentii , and T denticola by the end of the second year of maintenance. There was no consistent response to Capnucytophaga. When individual patient responses were examined. 6 of the 23 were found to have elevated titers to at least one of the microorganisms in the interval between pretreatment and the end of the hygienic phase; however, in all but one case, the titers at the end of the second year of maintenance were below pretreatment levels. Antibody levels to bacteria such as S. sanguis were modified during therapy. This would indicate that immune responses to microbes not generally considered to be “periodontal pathogens” may be modified by adjuvant activity associated with subgingival plaque or changes in the environment of the sulcus and that subsequent changes in titer do not necessarily reflect a role of that microorganism in the disease process. | en_US |
dc.format.extent | 3813010 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 1988 Munksgaard | en_US |
dc.subject.other | Periodontal Therapy | en_US |
dc.subject.other | Antibodies | en_US |
dc.subject.other | Plaque Microorganisms | en_US |
dc.subject.other | Immunoglobulins | en_US |
dc.subject.other | Longitudinal Study | en_US |
dc.title | The effects of periodontal therapy on serum antibody (IgG) levels to plaque microorganisms * | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Periodontics, The University of Michigan, Ann Arbor, Michigan 48109–0402, USA | en_US |
dc.contributor.affiliationum | Oral Biology, The University of Michigan, Ann Arbor, Michigan 48109–0402, USA | en_US |
dc.contributor.affiliationum | The Dental Research Institute, The University of Michigan, Ann Arbor, Michigan 48109–0402, USA | en_US |
dc.identifier.pmid | 3198782 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/75110/1/j.1600-051X.1988.tb02127.x.pdf | |
dc.identifier.doi | 10.1111/j.1600-051X.1988.tb02127.x | en_US |
dc.identifier.source | Journal of Clinical Periodontology | en_US |
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dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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