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Resuscitation Endpoints in Trauma

dc.contributor.authorNapolitano, Lena M.en_US
dc.date.accessioned2010-06-01T22:23:33Z
dc.date.available2010-06-01T22:23:33Z
dc.date.issued2005-03en_US
dc.identifier.citationNapolitano, Lena M. (2005). "Resuscitation Endpoints in Trauma." Transfusion Alternatives in Transfusion Medicine 6(4): 6-14. <http://hdl.handle.net/2027.42/75386>en_US
dc.identifier.issn1295-9022en_US
dc.identifier.issn1778-428Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75386
dc.description.abstractFluid and blood resuscitation is the mainstay of therapy for the treatment of hemorrhagic shock, whether due to trauma or other etiology. Cessation of hemorrhage with rapid hemostatic techniques is the first priority in the treatment of traumatic hemorrhagic shock, with concomitant fluid resuscitation with blood and crystalloids to maintain perfusion and organ function. “Hypotensive” or “low-volume” resuscitation has become increasingly accepted in the prehospital resuscitation phase of trauma, prior to definitive hemorrhage control, since aggressive fluid resuscitation may increase bleeding. Resuscitation after hemorrhage control is focused on restoration of tissue oxygenation. Efforts to optimize resuscitation have used “resuscitation endpoints” as markers of adequacy of resuscitation. The resuscitation endpoints that have been evaluated include both global (restoration of blood pressure, heart rate and urine output, lactate, base deficit, mixed venous oxygen saturation, ventricular end-diastolic volume) and regional (gastric tonometry, near-infrared spectroscopy for measurement of muscle tissue oxygen saturation) measures. This review critically evaluates the evidence regarding the use of resuscitation endpoints in trauma.en_US
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dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights2005 LMS Groupen_US
dc.subject.otherResuscitationen_US
dc.subject.otherEndpointsen_US
dc.subject.otherPerfusionen_US
dc.subject.otherTransfusionen_US
dc.subject.otherCrystalloiden_US
dc.subject.otherColloiden_US
dc.titleResuscitation Endpoints in Traumaen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelOncology and Hematologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumProfessor of Surgery University of Michigan School of Medicine Ann Arbor, Michigan, USAen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75386/1/j.1778-428X.2005.tb00127.x.pdf
dc.identifier.doi10.1111/j.1778-428X.2005.tb00127.xen_US
dc.identifier.sourceTransfusion Alternatives in Transfusion Medicineen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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