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DETECTION OF A t -COMPLEX ANTIGEN BY SECONDARY CELL-MEDIATED LYMPHOCYTOTOXICITY
dc.contributor.authorHammerberg, Craigen_US
dc.date.accessioned2010-06-01T22:39:08Z
dc.date.available2010-06-01T22:39:08Z
dc.date.issued1982-06en_US
dc.identifier.citationHammerberg, C. (1982). "DETECTION OF A t -COMPLEX ANTIGEN BY SECONDARY CELL-MEDIATED LYMPHOCYTOTOXICITY." International Journal of Immunogenetics 9(3): 179-184. <http://hdl.handle.net/2027.42/75626>en_US
dc.identifier.issn1744-3121en_US
dc.identifier.issn1744-313Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75626
dc.description.abstractBecause of the inconsistency in published results concerning the serological detection of cell surface antigens coded for by the t -complex, a cell-mediated lymphocytotoxicity (CML) assay, secondary CML, was used in a search for t -antigens. By sensitizing C3H. Ttf (C3H. Brachyury, tufted) with the congenic strain C3H. Ttf/t w18 splenic cells, a response against lipopolysaccharide (LPS) stimulated splenic cells from C3H. Ttf/t w18 mice is obtained. The locus coding for the antigen detected by this reaction lies to the left of tf on the murine seventeenth chromosome. The secondary CML response to this antigen is H-2 restricted and detects an antigen on all t -haplotypes tested: t w18 , t w18 tf, t 12 , t 6 , t h2 tf, and t w5 .en_US
dc.format.extent300391 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1982 Blackwell Scientific Publicationsen_US
dc.titleDETECTION OF A t -COMPLEX ANTIGEN BY SECONDARY CELL-MEDIATED LYMPHOCYTOTOXICITYen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMicrobiology and Immunologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Medical School, Ann Arbor, MI, U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75626/1/j.1744-313X.1982.tb00789.x.pdf
dc.identifier.doi10.1111/j.1744-313X.1982.tb00789.xen_US
dc.identifier.sourceInternational Journal of Immunogeneticsen_US
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dc.identifier.citedreferenceHammerberg, C. & Klein, J. ( 1975 ) Linkage disequilibrium between H-2 and t complexes in chromosome 17 of the mouse. Nature, 258, 296.en_US
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dc.identifier.citedreferenceYanagisawa, K., Bennett, D., Boyse, E.A., Dunn, L.C. & Dimeo, A. ( 1974 ) Serological identification of sperm antigens specified by lethal t-alleles in the mouse. Immunogenetics, 1, 57.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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