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Roles of residues 3 and 4 in cyclic tetrapeptide ligand recognition by the Κ -opioid receptor
dc.contributor.authorPrzydzial, M. J.en_US
dc.contributor.authorPogozheva, Irina D.en_US
dc.contributor.authorBosse, Kelly E.en_US
dc.contributor.authorAndrews, S. M.en_US
dc.contributor.authorTharp, T. A.en_US
dc.contributor.authorTraynor, John R.en_US
dc.contributor.authorMosberg, Henry I.en_US
dc.date.accessioned2010-06-01T22:45:22Z
dc.date.available2010-06-01T22:45:22Z
dc.date.issued2005-03en_US
dc.identifier.citationPrzydzial, M.J.; Pogozheva, I.D.; Bosse, K.E.; Andrews, S.M.; Tharp, T.A.; Traynor, J.R.; Mosberg, H.I. (2005). "Roles of residues 3 and 4 in cyclic tetrapeptide ligand recognition by the Κ -opioid receptor." The Journal of Peptide Research 65(3): 333-342. <http://hdl.handle.net/2027.42/75723>en_US
dc.identifier.issn1397-002Xen_US
dc.identifier.issn1399-3011en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/75723
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15787963&dopt=citationen_US
dc.format.extent243629 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights2005 Blackwell Munksgaarden_US
dc.subject.othercyclic peptidesen_US
dc.subject.otherG protein-coupled receptoren_US
dc.subject.otherΚ -opioid receptoren_US
dc.subject.otheropioid ligandsen_US
dc.titleRoles of residues 3 and 4 in cyclic tetrapeptide ligand recognition by the Κ -opioid receptoren_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.identifier.pmid15787963en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/75723/1/j.1399-3011.2005.00220.x.pdf
dc.identifier.doi10.1111/j.1399-3011.2005.00220.xen_US
dc.identifier.sourceThe Journal of Peptide Researchen_US
dc.identifier.citedreferenceMansour, A., Hoversten, M.T., Taylor, L.P., Watson, S.J. & Akil, H. ( 1995 ) The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 700, 89 – 98.en_US
dc.identifier.citedreferenceKieffer, B.L. ( 2000 ) Opioid receptors: from genes to mice. J. Pain 1 ( Suppl. 3 ), 45 – 50.en_US
dc.identifier.citedreferenceWatson, S. & Arkinstall, S. ( 1994 ) The G-protein Linked Receptor Facts Book. pp. 1 – 294. Academic Press, San Diego, USA.en_US
dc.identifier.citedreferenceFlower, D.R. ( 1999 ) Modeling G-protein-coupled receptors for drug design. Biochim. Biophys. Acta 1422, 207 – 234.en_US
dc.identifier.citedreferenceWaldhoer, M., Bartlett, S.E. & Whistler, J.L. ( 2004 ) Opioid receptors. Annu. Rev. Biochem. 73, 953 – 990.en_US
dc.identifier.citedreferencePalczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Teller, D.C., Okada, T., Stenkamp, R.E., Yamamoto, M. & Miyano, M. ( 2000 ) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289, 739 – 745.en_US
dc.identifier.citedreferenceLi, J., Edwards, P.C., Burghammer, M., Villa, C. & Schertler, G.F. ( 2004 ) Structure of bovine rhodopsin in a trigonal crystal form. J. Mol. Biol. 343, 1409 – 1438.en_US
dc.identifier.citedreferenceMosberg, H.I. & Fowler, C.B. ( 2002 ) Development and validation of opioid ligand-receptor interaction models: the structural basis of mu vs. delta selectivity. J. Pept. Res. 60, 329 – 335.en_US
dc.identifier.citedreferenceFowler, C., Pogozheva, I.D., Lomize, A.L., LeVine, H. III & Mosberg, H.I. ( 2004 ) Complex of and active Μ -opioid receptor with cyclic peptide agonist modeled from experimental constraints. Biochemistry 43, 15796 – 15810.en_US
dc.identifier.citedreferenceMosberg, H.I., Omnaas, J.R., Medzihradsky, F. & Smith, C.B. ( 1988 ) Cyclic, disulfide- and dithioether-containing opioid tetrapeptides: development of a ligand with high delta opioid receptor selectivity and affinity. Life Sci. 43, 1013 – 1020.en_US
dc.identifier.citedreferenceMosberg, H.I., Lomize, A.L., Wang, C., Kroona, H., Heyl, D.L., Ma, W., Sobczyk-Kojiro, K., Mousigian, C. & Porreca, F. ( 1994 ) Development of a model for the δ -opioid receptor pharmacophore: 1. Conformationally restricted Tyr 1 replacements in the cyclic δ receptor selective tetrapeptide Tyr-c[d-Cys-Phe-d-Pen]OH (JOM-13). J. Med. Chem. 37, 4371 – 4383.en_US
dc.identifier.citedreferenceMosberg, H.I., Omnaas, J.R., Lomize, A., Heyl, D.L., Nordan, I., Mousigian, C., Davis, P. & Porreca, F. ( 1994 ) Development of a model for the δ opioid receptor pharmacophore: 2. Conformationally restricted Phe 3 replacements in the cyclic δ -receptor selective tetrapeptide Tyr-c[d-Cys-Phe-d-Pen]OH (JOM-13). J. Med. Chem. 37, 4384 – 4391.en_US
dc.identifier.citedreferenceMosberg, H.I., Dua, R.K., Pogozheva, I.D. & Lomize, A.L. ( 1996 ) Development of a model for the δ opioid receptor pharmacophore: 4. Residue 3 dehydrophenyl-alanine analogs of Tyr-c[d-Cys-Phe-d-Pen]OH (JOM-13) confirm required gauche -orientation of aromatic side chain. Biopolymers 39, 287 – 296.en_US
dc.identifier.citedreferenceLomize, A.L., Flippen-Anderson, J.L., George, C. & Mosberg, H.I. ( 1994 ) Conformational analysis of the δ receptor-selective, cyclic opioid peptide, Tyr-c[d-Cys-Phe-d-Pen]OH (JOM-13). Comparison of X-ray crystallographic structures, molecular mechanics simulations and 1 H NMR data. J. Am. Chem. Soc. 116, 429 – 436.en_US
dc.identifier.citedreferenceHo, J.C. ( 1997 ) Development of a model for the δ -opioid receptor pharmacophore. PhD thesis, University of Michigan, Michigan, USA.en_US
dc.identifier.citedreferenceMcFadyen, I.J., Ho, J.C., Mosberg, H.I. & Traynor, J.R. ( 2000 ) Modifications of the cyclic mu receptor selective tetrapeptide Tyr-c[d-Cys-Phe-d-Pen]NH2 (Et): effects on opioid receptor binding and activation. J. Pept. Res. 55, 255 – 261.en_US
dc.identifier.citedreferenceFowler, C.B., Pogozheva, I.D., LeVine, H. III & Mosberg, H.I. ( 2004 ) Refinement of a homology model of the Μ -opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites. Biochemistry 43, 8700 – 8710.en_US
dc.identifier.citedreferencePortoghese, P.S. ( 1993 ) Selective nonpeptide opioid antagonists. In: Opioid I. ( Herz, A., ed. ), p. 279. Springer-Verlag, Berlin, Germany.en_US
dc.identifier.citedreferenceMeng, F., Hoversten, M.T., Thompson, R.C., Taylor, L., Watson, S.J. & Akil, H. ( 1995 ) A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains. J. Biol. Chem. 270, 12730 – 12736.en_US
dc.identifier.citedreferenceMetzger, T.G. & Ferguson, D.M. ( 1995 ) On the role of extracellular loops of opioid receptors in conferring ligand selectivity. FEBS Lett. 375, 1 – 4.en_US
dc.identifier.citedreferencePogozheva, I.D., Lomize, A.L. & Mosberg, H.I. ( 1998 ) Opioid receptor three-dimensional structures from distance geometry calculations with hydrogen bonding constraints. Biophys. J. 75, 612 – 634.en_US
dc.identifier.citedreferenceLomize, A.L., Pogozheva, I.D. & Mosberg, H.I. ( 1999 ) Structural organization of G-protein-coupled receptors. J. Comput. Aided Mol. Des. 13, 325 – 353.en_US
dc.identifier.citedreferencePoulsen, A., Bjornholm, B., Gundertofte, K., Pogozheva, I.D. & Liljefors, T. ( 2003 ) Pharmacophore and receptor models for neurokinin receptors. J. Comput. Aided Mol. Des. 17, 765 – 783.en_US
dc.identifier.citedreferenceMunshi, U.M., Pogozheva, I.D. & Menon, K.M. ( 2003 ) Highly conserved serine in the third transmembrane helix of the luteinizing hormone/human chorionic gonadotropin receptor regulates receptor activation. Biochemistry 42, 3708 – 3715.en_US
dc.identifier.citedreferenceStrahs, D. & Weinstein, H. ( 1997 ) Comparative modeling and molecular dynamics studies of the delta, kappa and mu opioid receptors. Protein Eng. 10, 1019 – 1038.en_US
dc.identifier.citedreferencePaterlini, G., Portoghese, P.S. & Ferguson, D.M. ( 1997 ) Molecular simulation of dynorphin A-(1–10) binding to extracellular loop 2 of the kappa-opioid receptor. A model for receptor activation. J. Med. Chem. 40, 3254 – 3262.en_US
dc.identifier.citedreferenceSubramanian, G., Paterlini, M.G., Larson, D.L., Portoghese, P.S. & Ferguson, D.M. ( 1998 ) Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. J. Med. Chem. 41, 4777 – 4789.en_US
dc.identifier.citedreferenceLiu, D.X., Jiang, H.L., Shen, J.S., Zhu, W.L., Zhao, L., Chen, K.X. & Ji, R.Y. ( 1999 ) Molecular modeling on kappa opioid receptor and its interaction with nonpeptide kappa opioid agonists. Zhongguo Yao Li Xue Bao 20, 131 – 136.en_US
dc.identifier.citedreferenceLavecchia, A., Greco, G., Novellino, E., Vittorio, F. & Ronsisvalle, G. ( 2000 ) Modeling of kappa-opioid receptor/agonists interactions using pharmacophore-based and docking simulations. J. Med. Chem. 43, 2124 – 2134.en_US
dc.identifier.citedreferenceIadanza, M., Holtje, M., Ronsisvalle, G. & Holtje, H.D. ( 2002 ) Κ -Opioid receptor model in a phospholipid bilayer: molecular dynamics simulation. J. Med. Chem. 45, 4838 – 4846.en_US
dc.identifier.citedreferenceWan, X.H., Huang, X.Q., Zhou, D.H., Jiang, H.L., Chen, K.X. & Chi, Z.Q. ( 2000 ) Building 3D-structural model of kappa opioid receptor and studying its interaction mechanism with dynorphin A(1–8). Acta Pharmacol. Sin. 21, 701 – 708.en_US
dc.identifier.citedreferenceFilizola, M., Laakkonen, L. & Loew, G.H. ( 1999 ) 3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors. Protein Eng. 12, 927 – 942.en_US
dc.identifier.citedreferenceSanchez, R., Pieper, U., Mirkovic, N., de Bakker, P.I., Wittenstein, E. & Sali, A. ( 2000 ) MODBASE, a database of annotated comparative protein structure models. Nucleic Acids Res. 28, 250 – 253.en_US
dc.identifier.citedreferenceMcFadyen, I.J., Schaefer, M.J., Ho, J.C., Omnaas, J.R., Sobczyk-Kojiro, K., Mosberg, H.I. & Traynor, J.R. ( 2000 ) Tetrapeptide derivatives of DPDPE lacking an N-terminal tyrosine residue are agonists at the mu opioid receptor. J. Pharmacol. Exp. Ther. 295, 960 – 966.en_US
dc.identifier.citedreferenceNeilan, C.L., Husbands, S.M., Breeden, S., Ko, M.C., Aceto, M.D., Lewis, J.W., Woods, J.H. & Traynor, J.R. ( 2004 ) Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist. Eur. J. Pharmacol. 499, 107 – 111.en_US
dc.identifier.citedreferenceGÜntert, P., Brawn, W. & WÜthrich, K. ( 1991 ) Efficient computation of three-dimensional protein structure in solution from NMR data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA. J. Mol. Biol. 21, 517 – 530.en_US
dc.identifier.citedreferencePogozheva, I.D., Lomize, A.L. & Mosberg, H.I. ( 1997 ) The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints. Biophys. J. 72, 1963 – 1985.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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