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Effect of somatic mutation on DNA binding properties of anti-DNA autoantibodies
(Wiley Subscription Services, Inc., A Wiley Company, 2007-04-05)
Autoantibodies that bind DNA are a hallmark of systemic lupus erythematosus. A subset of autoantibody•DNA complexes localize to kidney tissue and lead to damage and even death. 11F8, 9F11, and 15B10 are clonally related ...