Now showing items 1-10 of 10
Ornithine decarboxylase activity in retinal explants of goldfish undergoing optic nerve regeneration
(Elsevier, 1981-06)
Retinal explants cultured in the presence of fetal calf serum (FCS) exhibit an increase in the activity of ornithine decarboxylase which is maximal several hours after explanation. The measured activity of this enzyme is ...
Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1985-08)
The calcium-activated phosphodiesteratic hydrolysis of 32 P-labeled phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate in prelabeled nerve ending membranes is inhibited by the aminoglycosides neomycin ...
Increased activity of ornithine decarboxylase in goldfish following optic nerve crush
(Elsevier, 1981-06)
Ornithine decarboxylase (ODC) activity increased in goldfish retina, brain, and kidney several days following unilateral intraorbital optic nerve crush. Activity in both retinas followed a similar time course, an elevation ...
Properties of endogenous, membrane-associated sialidase activity (N-acetylneuraminidase) of the goldfish visual system
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1983-01)
The endogenous sialidase (N-acetylneuraminidase) activity of membranes prepared from goldfish retina and optic tectum displays characteristics similar to those reported for neural plasma membrane sialidases of other ...
Protein synthesis and transport in the regenerating goldfish visual system
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1982-06)
The nature of the proteins synthesized in the goldfish retina and axonally transported to the tectum during optic nerve regeneration has been examined. Electrophoretic analysis of labeled soluble retinal proteins by ...
Anticonvulsant activity of cyclopentano amino acids
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1980-01)
The hypothesis that certain amino acid analogues possessing a five-membered ring structure or amino acid analogues that can be viewed as fragments derived from such a ring would have anticonvulsant activity was proposed ...
Studies on the localization of newly added membrane in growing neurites
(Wiley Subscription Services, Inc., A Wiley Company, 1981-11)
Explant culture of the adult goldfish retina results in vigorous neuritic growth, provided that the optic nerve has been previously crushed in vivo. The site of new membrane addition in these growing neurites was studied ...
The retina as a biochemical model of central nervous system regeneration
(Elsevier, 1980)
The visual system of primitive vertebrates has long served as a useful model for the resynthesis of damaged neurons. The prior optic nerve crush imparts a marked tendency on the part of cultured retinal explants to extend ...
Laminin supports neurite outgrowth from explants of axotomized adult rat retinal neurons
(Elsevier, 1986-07)
The influence of laminin on neurite outgrowth from explants of adult rat retina and its distribution in normal and lesioned rat optic nerves were examined. Neurite outgrowth required the presence of laminin in the substratum, ...
Dissociation of enhanced ornithine decarboxylase activity and optic nerve regeneration in goldfish
(Elsevier, 1982-06)
The significance of a previously observed increase in retinal ornithine decarboxylase (ODC, EC 4.1.1.17) following optic nerve crush was investigated in goldfish using a specific irreversible inhibitor of ODC, [alpha]-di ...