Now showing items 1-10 of 21
Ornithine decarboxylase activity in retinal explants of goldfish undergoing optic nerve regeneration
(Elsevier, 1981-06)
Retinal explants cultured in the presence of fetal calf serum (FCS) exhibit an increase in the activity of ornithine decarboxylase which is maximal several hours after explanation. The measured activity of this enzyme is ...
Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1985-08)
The calcium-activated phosphodiesteratic hydrolysis of 32 P-labeled phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate in prelabeled nerve ending membranes is inhibited by the aminoglycosides neomycin ...
Increased activity of ornithine decarboxylase in goldfish following optic nerve crush
(Elsevier, 1981-06)
Ornithine decarboxylase (ODC) activity increased in goldfish retina, brain, and kidney several days following unilateral intraorbital optic nerve crush. Activity in both retinas followed a similar time course, an elevation ...
Properties of endogenous, membrane-associated sialidase activity (N-acetylneuraminidase) of the goldfish visual system
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1983-01)
The endogenous sialidase (N-acetylneuraminidase) activity of membranes prepared from goldfish retina and optic tectum displays characteristics similar to those reported for neural plasma membrane sialidases of other ...
Regulation of Myo-Inositol Homeostasis in Differentiated Human NT2-N Neurons
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2000-05)
We have investigated the possible role of second messengers on inositol homeostasis in NT2-N cells, human central nervous system neurons obtained by terminal differentiation of teratocarcinoma precursors. Uptake of inositol ...
Substitution of D-Trp 32 in NPY Destabilizes the Binding Transition State to the Y1 Receptor Site in SK-N-MC Cell Membranes
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1997-04)
The retention rate of the spin label 3-isothiocyanto methyl-2,2,5,5-tetramethyl-1-pyrrolidinyl oxyl spin label (proxyl) attached to the porcine N-acetyl-NPY peptide and the porcine N-acetyl-D-Trp 32 -NPY peptide at Lys 4 ...
Protein synthesis and transport in the regenerating goldfish visual system
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1982-06)
The nature of the proteins synthesized in the goldfish retina and axonally transported to the tectum during optic nerve regeneration has been examined. Electrophoretic analysis of labeled soluble retinal proteins by ...
Anticonvulsant activity of cyclopentano amino acids
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1980-01)
The hypothesis that certain amino acid analogues possessing a five-membered ring structure or amino acid analogues that can be viewed as fragments derived from such a ring would have anticonvulsant activity was proposed ...
Expression of Corticotropin-Releasing Hormone Transgenes in Neurons of Adult and Developing Mice
(Elsevier, 1994-12)
The DNA sequences important for cell-specific expression and developmental regulation of corticotropin-releasing hormone (CRH) were analyzed in transgenic mice. A construct containing 0.5 kb of CRH 5' flanking DNA linked ...
Age-dependent changes in the specificity of tRNA methyltransferases in the cerebellum of the icteric and nonicteric Gunn rat
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1979-10)
The activity of tRNA methyltransferases present in the cerebellum of 6- and 21-day-old nonicteric and icteric Gunn rats was compared using purified E. coli tRNAs as substrates. At 6 days the tRNA methyltransferases of the ...