Now showing items 1-10 of 28
Esophageal involvement in epidermolysis bullosa dystrophica: Clinical and roentgenographic manifestations
(Springer-Verlag, 1983-12)
Epidermolysis bullosa is a rare hereditary mechanobullous skin disorder. Four patients with esophageal involvement are reported. These cases and review of reported cases of epidermolysis bullosa dystrophica-recessive (EBD-R) ...
A psychocutaneous profile of psoriasis patients who are stress reactors : A study of 127 patients
(Elsevier, 1989-05)
Psoriasis is a chronic, relapsing, cutaneous condition with a 1%-2% prevalence in the general population. About 40% of psoriatics report that psychosocial stress significantly exacerbates their condition. However, the ...
Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-Α production in keratinocytes cultured from psoriatic lesions
(Blackwell Publishing Ltd, 1989-08)
Keratinocytes from involved psoriatic plaques (PP), uninvolved, clinically symptomless skin of psoriatic patients (PN) and normal healthy skin (NN) have been cultured in a low calcium serum free system for multiple passages. ...
A new syndrome of axial muscle rigidity associated with etretinate therapy A videotape segment accompanies this article.
(Wiley Subscription Services, Inc., A Wiley Company, 1988)
We report on three cases of a novel syndrome associated with treatment for psoriasis with the retinoid etretinate. The distinctive features of this syndrome include rigidity that is restricted to the axial muscles, impairment ...
GTP[gamma]S-stimulated hydrolysis of phosphatidyinositol-4,5-bisphosphate by soluble phospholipase C from human platelets requires soluble GTP-binding protein
(Elsevier, 1988-07-15)
GTP-binding activity was fractionated into two peaks (GI and GII) by chromatography on heparin-agarose. GTP-dependent PLC activity eluted as a single peak, which co-chromatographed with GTP-binding peak GII. Rechromatography ...
Differential activation of human skin cells by platelet activating factor: Stimulation of phosphoinositide turnover and arachidonic acid mobilization in keratinocytes but not in fibroblasts
(Elsevier, 1989-09-29)
Treatment of cultured adult human keratinocytes with platelet activating factor (PAF) resulted in a rapid, dose dependent accumulation of inositol phosphates. Inositol trisphosphate (IP3), inositol bisphosphate (IP2) and ...
Cyclosporine A
(Elsevier, 1989)
Cyclosporine A (CsA) is a neutral lipophilic compound that was first isolated in the 1970s from the fungal species Tolypocladium inflatum gams. CsA is a cyclic polypeptide that consists of 11 amino acids and that has a ...
Nifedipine in Scleroderma Ulcerations
(Blackwell Publishing Ltd, 1984-12)
Cutaneous ulcerations may be due to a variety of causes, including vasculitis. infections, arterial insufficiency, and microvascular damage. The net effect is diminished blood flow to the skin. Nifedipine, a calcium ...
Leukotrienes B 4 , C 4 and D 4 stimulate DNA synthesis in cultured human epidermal keratinocytes
(Blackwell Publishing Ltd, 1985-07)
Leukotrienes in psoriatic skin lesions are potent mediators of inflammation. We have studied the capacity of leukotrienes to stimulate the DNA synthesis of cultured human epidermal keratinocytes. At concentrations ranging ...