Now showing items 1-10 of 58
Amino acid substitution and chemical characterization of a Japanese variant of carbonic anhydrase I: CA I Hiroshima-1 (86 Asp → Gly)
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1981-06)
An electrophoretic variant of red cell carbonic anhydrase I, designated CA I Hiroshima-1, has been observed in 12 apparently unrelated individuals during a survey of 13,019 individuals from the cities of Hiroshima and ...
Hormonal regulation of plasminogen activator in rat hepatoma cells
(Kluwer Academic Publishers; Martinus Nijhoff Publishers ; Springer Science+Business Media, 1983-03)
Plasminogen activators are membrane-associated, arginine-specific serine proteases which convert the inactive plasma zymogen plasminogen to plasmin, an active, broad-spectrum serine protease. Plasmin, the major fibrinolytic ...
Linkage of the structural gene for uroporphyrinogen I synthase to markers on mouse chromosome 9 in a cross between feral and inbred mice
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1982-08)
The Ups locus has been mapped to mouse chromosome 9 in a three-point cross. The observed gene order is centromere- Ups -15- Mpi-1 -22- Mod-1 . Ups is unlinked to Lv , which encodes the previous enzyme in the heme biosynthesis ...
DNA polymorphism in the 5′ flanking region of the human carbonic anhydrase II gene on chromosome 8
(Springer-Verlag, 1985-04)
A restriction-fragment-length polymorphism (RFLP) is described which is associated with the human carbonic anhydrase II gene ( CA2 ) that codes for one of the three genetically distinct carbonic anhydrase isozymes, CA I, ...
Modification of cell membrane in variants of chinese hamster cells resistant to abrin
(Elsevier, 1980-10)
Stable and heritable variants of Chinese hamster ovary (CHO) cells which are resistant to different levels (0.1, 1.0 and 10 [mu]g/ml) of the toxin abrin have been isolated and characterized. The frequency of resistant ...
Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection
(Elsevier, 1985-04-30)
A series of survivor cell lines derived by infection of B103 rat neuroma cells with active wild-type herpes simplex virus type 1 (HSV-1) (M. Levine, A. L. Goldin, and J. C. Glorioso, J. Virol. 35, 203-210 (1980)) has been ...
Herpes simplex virus thymidine kinase gene is stably maintained and expressed in cells transformed by protoplast fusion
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1984-03)
We examined a series of transformed cell lines resulting from transfer of the herpes simplex virus type 1 thymidine kinase gene to Ltk − cells by protoplast fusion gene transfer. We show that multiple copies of the ...
Activation of mammalian skeletal-muscle carbonic anhydrase III by arginine modification
(Kluwer Academic Publishers; The Biochemical Society ; Springer Science+Business Media, 1984-07)
Purified carbonic anhydrase isozymes I, II, and III (CA I, CA II, CA III) from various sources were treated with 2,3-butanedione and their bicarbonate dehydration reactions followed. The specific activities of human and ...
Inhibition of glycosylation of herpes simplex virus glycoproteins: Identification of antigenic and immunogenic partially glycosylated glycopeptides on the cell surface membrane
(Elsevier, 1983-04-15)
The surface membranes of cells infected with herpes simplex virus type 1 (HSV-1), strain KOS, contain three principal glycoproteins, gC (apparent Mr 129k), gB (apparent Mr 120k), and gD (apparent Mr 58k). Infections carried ...
Evaluation of methods for the estimation of mutation rates in cultured mammalian cell populations
(Elsevier, 1987-04)
A systematic comparison of 5 different statistical methods for the estimation of mutation rate ([mu]) in cultured Chinese hamster V79 cells is presented. Fluctuation tests were performed with several large batches of ...