Now showing items 1-10 of 22
Hormonal regulation of plasminogen activator in rat hepatoma cells
(Kluwer Academic Publishers; Martinus Nijhoff Publishers ; Springer Science+Business Media, 1983-03)
Plasminogen activators are membrane-associated, arginine-specific serine proteases which convert the inactive plasma zymogen plasminogen to plasmin, an active, broad-spectrum serine protease. Plasmin, the major fibrinolytic ...
DNA polymorphism in the 5′ flanking region of the human carbonic anhydrase II gene on chromosome 8
(Springer-Verlag, 1985-04)
A restriction-fragment-length polymorphism (RFLP) is described which is associated with the human carbonic anhydrase II gene ( CA2 ) that codes for one of the three genetically distinct carbonic anhydrase isozymes, CA I, ...
Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection
(Elsevier, 1985-04-30)
A series of survivor cell lines derived by infection of B103 rat neuroma cells with active wild-type herpes simplex virus type 1 (HSV-1) (M. Levine, A. L. Goldin, and J. C. Glorioso, J. Virol. 35, 203-210 (1980)) has been ...
Inhibition of glycosylation of herpes simplex virus glycoproteins: Identification of antigenic and immunogenic partially glycosylated glycopeptides on the cell surface membrane
(Elsevier, 1983-04-15)
The surface membranes of cells infected with herpes simplex virus type 1 (HSV-1), strain KOS, contain three principal glycoproteins, gC (apparent Mr 129k), gB (apparent Mr 120k), and gD (apparent Mr 58k). Infections carried ...
Evaluation of methods for the estimation of mutation rates in cultured mammalian cell populations
(Elsevier, 1987-04)
A systematic comparison of 5 different statistical methods for the estimation of mutation rate ([mu]) in cultured Chinese hamster V79 cells is presented. Fluctuation tests were performed with several large batches of ...
Reactivation and immunological studies on a japanese variant of red cell carbonic anhydrase I, CA I hiroshima-1
(Elsevier, 1982)
1. 1. Under certain conditions, CA I HIR-1++ (86 Asp--> Gly) was inactivated in Gnd-HCl more rapidly than normal CA I.2. 2. After denaturation in 5.0 M Gnd [middle dot] HC1, CA I HIR-1 was reactivated more slowly than ...
Apparent synergism between amino donors for CTP synthesis in Chinese hamster fibroblasts
(Kluwer Academic Publishers; Martinus Nijhoff Publishers ; Springer Science+Business Media, 1983-09)
The synergistic effects of potential amino donors were studied in the assay of CTP synthetase in extracts of Chinese hamster fibroblasts. We found that L-glutamine was not effective as the sole amino donor, but combinations ...
A deterministic approach for the estimation of mutation rates in cultured mammalian cells
(Elsevier, 1985-03)
Unequal growth rates between mutant and wild-type cells in a large population constitute a problem for the estimation of mutation rate. Over a period of cell growth, a selective advantage of one cell type over the other ...
Paradoxical effects of glucocorticoids on regulation of plasminogen activator activity : Mediation by glucocorticoid receptors
(Elsevier, 1984-02)
Dexamethasone, a synthetic glucocorticoid, decreases the plasminogen activator (PA) activity of HTC rat hepatoma cells in tissue culture. Paradoxically, dexamethasone enhances the cyclic nucleotide stimulation of PA activity ...
Insulin resistance in H-35 rat hepatoma cells is mediated by post-receptor mechanisms
(Elsevier, 1983-09)
Incubation of H-35 cells with 300 ng/ml (50 nM) of insulin causes a 3-4-fold induction of tyrosine aminotransferase at 4-6 h of incubation. At 24 h the activity of transaminase returns to basal levels despite the presence ...