Now showing items 41-50 of 660
Bim--Bcl-2 Homology 2 Mimetic Therapy in Effective at Suppressing Inflammatory Arthritis Through the Activation of Myeloid Cell Apoptosis
(American College of Rheumatology, 2010-02)
Objective: Rheumatoid arthritis (RA) is a destructive autoimmune disease characterized by an increased inflammation in the joint. Therapies that activate the apoptotic cascade may have potential for use in RA; however, few ...
Intracellular acidosis: Can it delay the inevitable?
(W.B. SaundersWiley Periodiocals, Inc., 1990-04)
The relationships between extracellular pH (pH o ), intracellular pH (pH i ), and loss of cell viability were evaluated in cultured rat hepatocytes after ATP depletion by metabolic inhibition with KCN and iodoacetate ...
Concurrent expression of procoagulant and plasminogen activator activities by rabbit alveolar macrophages in vitro: Opposite modulating effects of prostaglandin E2
(Elsevier, 1988-09-01)
We examined the effects of arachidonic acid metabolites on the simultaneous expression of procoagulant (PC) and plasminogen activator (PA) activities by rabbit alveolar macrophages. Incubation with lymphocyte-conditioned ...
Protein C deficiency and acute myocardial infarction in the third decade
(Elsevier, 1991-07-01)
Protein C deficiency has been associated with a predisposition to venous thrombosis and thromboembolism. Arterial thrombosis has been seen much less frequently and may require other vascular risk factors. Here we describe ...
Phenotypic heterogeneity between different mutations of MODY subtypes and within MODY pedigrees
(Springer-Verlag, 2006-05)
New insights into canalicular organic anion secretion
(W.B. SaundersWiley Periodiocals, Inc., 1991-01)
The effect of partial and complete dissipation of the membrane potential and partial depletion of cellular ATP content on the efflux of dinitrophenyl-glutathione and oxidized glutathione was examined in hepatocytes isolated ...
Leucocytoclastic Vasculitis (Hypersensitivity Angiitis) of the Small Bowel Presenting with Severe Gastrointestinal Hemorrhage
(Blackwell Publishing Ltd, 1986-03)
Bile acid transport: Lessons from the intestine
(W.B. SaundersWiley Periodiocals, Inc., 1987-03)
The transport of bile acid was studied in basolateral membrane vesicles isolated from rat small intestine. Taurocholate transport into an osmotically reactive intravesicular space was Na + independent. The uptake of ...
Atrial Pacing During a Narrow QRS Complex Tachycardia: What is the Mechanism?
(Blackwell Science Inc, 2002-03)