Now showing items 31-40 of 236
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
(Kluwer Academic Publishers; Springer, 2005-06)
Tamoxifen has been a mainstay of adjuvant therapy for breast cancer for many years. We sought to determine if genetic variability in the tamoxifen metabolic pathway influenced overall survival in breast cancer patients ...
Are Physician Reimbursement Strategies Associated with Processes of Care and Patient Satisfaction for Patients with Diabetes in Managed Care?
(Blackwell Publishing Inc, 2006-08)
To examine associations between physician reimbursement incentives and diabetes care processes and explore potential confounding with physician organizational model. Data Sources . Primary data collected during 2000–2001 ...
RhoC Induces Differential Expression of Genes Involved in Invasion and Metastasis in MCF10A Breast Cells
(Kluwer Academic Publishers; Springer Science+Business Media, 2004-03)
Inflammatory breast cancer (IBC) is the most deadly form of breast cancer in humans presumably due to its ability to metastasize from its inception. In our laboratory, overexpression of RhoC GTPase was observed to be ...
Psychosocial factors influence control of moderate and severe hypertension
(Elsevier, 1983)
Factors affecting the degree of blood pressure control achieved by antihypertensive drug treatment in 150 patients with moderate and severe essential hypertension were analyzed. Patients were under continuing treatment for ...
The binding of somatostatin to the mouse retina is altered by the pearl mutation
(Elsevier, 1990-07-09)
Pearl mutants have a night-blind phenotype and abnormal optokinetic nystagmus. Preliminary results from another study14 showed that the light responses of retinal ganglion cells of pearl mutant mice were affected by bathing ...
Rapid Re-expansion of a Macroprolactinoma After Early Discontinuation of Bromocriptine
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-11)
Prolactin (PRL)-secreting pituitary adenomas are the most common functioning pituitary tumors. Medical treatment with dopamine agonists is the therapy of choice for macroprolactinomas (≥10 mm). Withdrawal of bromocriptine ...
Transcript identification in the BRCA1 candidate region
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-02)
Chromosome 17q12-21 is known to contain a gene (or genes) which confers susceptibility to early-onset breast cancer and ovarian cancer (BRCA1). Identification and isolation of BRCA1 will likely provide the basis for increased ...
Pergolide As Primary Therapy for Macroprolactinomas
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-12)
The objective of this study is to determine whether pergolide therapy is an effective modality for the de novo treatment of patients with macroprolactinomas. Twenty-two consecutive patients with macroprolactinomas were ...
Distal chromosome 17q loss in Barrett's esophageal and gastric cardia adenocarcinomas: Implications for tumorigenesis
(John Wiley & Sons, Inc., 1998-08)
The molecular genetic mechanisms underlying esophageal cancer are poorly understood. However, a novel gene that may be involved in esophageal carcinogenesis was recently localized by others to distal 17q by linkage analysis ...