Now showing items 1-10 of 82
7 th HUPO World Congress of Proteomics: Launching the Second Phase of the HUPO Plasma Proteome Project (PPP-2) 16–20 August 2008, Amsterdam, The Netherlands
(WILEY-VCH Verlag, 2009-01)
The HUPO Plasma Proteome Project new phase, PPP-2, held its initial workshop on 17 August, 2008, at the 7 th World Congress of Proteomics in Amsterdam. Technology platforms, data repositories, informatics, and engagement ...
CCK antagonists reveal that CCK-8 and JMV-180 interact with different sites on the rat pancreatic acinar cell CCKA receptor
(Elsevier, 1994)
The ability of CCKA antagonists to inhibit full and partial CCK agonists of the rat pancreatic acinar cell CCKA receptor has been studied. When isolated rat pancreatic acini were superfused with CCK-8 (10 pM-1 nM) or CCK-4 ...
Binding of Griffonia simplicifolia I lectin to rat pulmonary alveolar macrophages and its use in purifying type II alveolar epithelial cells
(Elsevier, 1986-01-23)
We report that the isolectin Griffonia simplicifolia I-B4 isolated from G. simplicifolia seeds binds to rat alveolar macrophages present in frozen sections of lung tissue or bronchoalveolar lavage fluid. G. simplicifolia ...
Interactions of intracellular mediators of amylase secretion in permeabilized pancreatic acini
(Elsevier, 1991-01-23)
Mouse pancreatic acini were permeabilized with streptolysin O to investigate amylase secretion stimulated by various intracellular mediators and the kinetics of secretion as a function of temperature. Amylase secretion was ...
Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase
(Elsevier, 1994-04-25)
Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase. The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.
Stimulation by prostaglandin E2 of glucagon and insulin release from isolated rat pancreas
(Elsevier, 1975-09)
To ascertain whether prostaglandins (PG) may play a role in the secretion of glucagon and in an attempt to elucidate the conflicting observations on the effects of PG on insulin release, the isolated intact rat pancreas ...
Augmentation of hepatic doxorubicin extraction with extracorporeal filtration avoids the dose-dependent, nonlinear increase in AUC observed with systemic administration
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1997-12)
Purpose : Regional therapy of primary or metastatic liver cancer with low hepatic extraction ratio drugs such as doxorubicin is constrained by development of systemic toxicity. To examine the effect of augmentation of ...
Agarose drop method for loading thin polyacrylamide gels
(Elsevier, 1982-11-01)
The gels (<1 mm) can be loaded conveniently, rapidly, and quantitatively by suspending the sample to be analyzed in a drop of agarose gel and simply placing the solidified drop on top of the stacking gel. With this ...
Chemotherapy for prostate cancer: implementing early systemic therapy to improve outcomes
(Springer-Verlag, 2005-11)
Prostate cancer remains a significant health concern for men in the USA as it is a leading cancer diagnosis and a cause of death. With the use of prostate-specific antigen or screening, a stage migration has occurred with ...