Now showing items 11-20 of 173
Repression of motility during fimbrial expression: identification of 14 mrpJ gene paralogues in Proteus mirabilis
(Blackwell Publishing Ltd, 2008-07)
Proteus mirabilis alternates between motile and adherent forms. MrpJ, a transcriptional regulator previously reported to repress motility, is encoded at the 3′ end of the mrp fimbrial operon in P. mirabilis . Sequencing ...
Optimal design of feedback control by inhibition
(Springer-Verlag, 1974-06)
A recently developed, nonlinear method of systems analysis has been used to compare alternative patterns of control by feedback inhibition in otherwise equivalent unbranched biosynthetic pathways. The steady state performance ...
Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence
(Blackwell Publishing Ltd, 2009-03)
During its life cycle, Legionella pneumophila alternates between at least two phenotypes: a resilient, infectious form equipped for transmission and a replicative cell type that grows in amoebae and macrophages. Considering ...
Checkpoints and restriction points in bacteria and eukaryotic cells
(Wiley Subscription Services, Inc., A Wiley Company, 2006-10)
Bacterial checkpoints, analogous to those proposed to exist in eukaryotic cells, offer insights into the definition of a checkpoint. Examination of bacterial “checkpoint” or arrest phenomena illustrate problems with a ...
Analysis of ToxR-dependent transcription activation of ompU , the gene encoding a major envelope protein in Vibrio cholerae
(Blackwell Science Ltd, UK, 1998-07)
Tn917 transposase. Sequence correction reveals a single open reading frame corresponding to the tnpA determinant of Tn3-family elements
(Elsevier, 1991-03)
A nucleotide sequence correction on the Enterococcus faecalis transposon Tn917 indicates that what was formerly thought to be two open reading frames (ORF5 and ORF6) is actually one reading frame (ORF5). The latter exhibits ...
Transcriptional control of toxT , a regulatory gene in the ToxR regulon of Vibrio cholerae
(Blackwell Publishing Ltd, 1994-10)
Co-ordinate expression of many virulence genes in Vibrio cholerae is under the control of the ToxR and ToxT proteins. These proteins function in a regulatory cascade in which ToxR is required to activate toxT , and ToxT ...
Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein
(Blackwell Science Ltd, 2002-07)
The Enterococcus faecalis conjugative plasmids pAD1 and pAM373 encode a mating response to the peptide sex pheromones cAD1 and cAM373 respectively. Sequence determination of both plasmids has recently been completed with ...
Synthesis of the Tetraketide Lactones from the Pikromycin Biosynthetic Pathway
(WILEY-VCH Verlag, 2007-07)
Synthesis of tetraketide lactones 2 and 3 , which are likely to be produced by a model pikromycin polyketide synthase (PKS), has been investigated. The tetraketide lactones with six-membered rings, 2a and 2b , were ...
Activation of both acfA and acfD transcription by Vibrio cholerae ToxT requires binding to two centrally located DNA sites in an inverted repeat conformation
(Blackwell Science Ltd, 2005-05)
The Gram-negative bacterium Vibrio cholerae is the infectious agent responsible for the disease Asiatic cholera. The genes required for V. cholerae virulence, such as those encoding the cholera toxin (CT) and toxin-coregulated ...