Now showing items 71-80 of 173
A criterion for using chloramphenicol to define different processes in the initiation of DNA synthesis in bacteria
(Elsevier, 1974-07)
A criterion is proposed which must be met in order to demonstrate that two different proteins are required for the initiation of DNA synthesis, with each protein being synthesized at a different time prior to initiation, ...
Feedforward inhibition in biosynthetic pathways: inhibition of the aminoacyl-tRNA synthetase by intermediates of the pathway
(Elsevier, 1979-04-21)
The stability of an amino acid biosynthetic pathway controlled by end-product inhibition is significantly improved if, in addition, the corresponding aminoacyl-tRNA synthetase is inhibited by an intermediate in the pathway. ...
A comparison of variant theories of intact biochemical systems. I. enzyme-enzyme interactions and biochemical systems theory
(Elsevier, 1989-06)
The need for a well-structured theory of intact biochemical systems becomes increasingly evident as one attempts to integrate the vast knowledge of individual molecular constituents, which has been expanding for several ...
Evidence that a nucleotide sequence, "boxA," is involved in the action of the NusA protein
(Elsevier, 1983-08)
We report the isolation of a mutation, boxA 1, in the nutR region of the phage [lambda] genome. The nutR region, located downstream of the pR promoter, includes the site nutR where the [lambda] N protein is thought to act ...
Optimization of kinetic proofreading: A general method for derivation of the constraint relations and an exploration of a specific case
(Elsevier, 1981-11-07)
We have previously presented a general cost-accuracy relationship for a broad class of kinetic proofreading mechanisms. In this paper we present a general matrix method, based upon classical enzyme kinetics, for the ...
Positive regulatory gene for temperature-controlled proteins in Escherichia coli
(Elsevier, 1981-05-29)
SummaryA group of nine proteins of Escherichia coli K12 vary in steady state level with growth temperature, and are particularly abundant above 40[deg]C. The identities of most of these HTP (high temperature production) ...
The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT
(Blackwell Science Ltd, 2006-03)
The Gram-negative, curved rod Vibrio cholerae causes the severe diarrhoeal disease cholera. The two major virulence factors produced by V. cholerae during infection are the cholera toxin (CT) and the toxin-coregulated pilus ...
FV-1 restriction of age-dependent paralytic lactic dehydrogenase virus infection
(Elsevier, 1982-02)
A genetic analysis was made of the susceptibility of inbred mice to a paralytic disease elicited by the ip injection of a neuroparalytic strain of lactic dehydrogenase virus. The frequency of disease in susceptible inbred ...
Cloning, mapping and nucleotide sequencing of a gene encoding a universal stress protein in Eschericha coli
(Blackwell Publishing Ltd, 1992-11)
The response of non-differentiating bacteria to nutrient starvation is complex and includes the sequential synthesis of starvation-inducible proteins. Although starvation for different individual nutrients generally provokes ...