Now showing items 1-10 of 27
The multiple sleep latency test and Epworth sleepiness scale in the assessment of daytime sleepiness
(Blackwell Science Ltd, 2000-12-18)
Qualitative Data Collection and Analysis Methods: The INSTINCT Trial
(Blackwell Publishing Ltd, 2007-11)
Mechanisms and functional significance of aberrant seizure-induced hippocampal neurogenesis
(Blackwell Publishing Inc, 2008-06)
Studies of experimental mesial temporal lobe epilepsy (mTLE) indicate that prolonged seizures in the adult not only damage the hippocampal formation but also dramatically stimulate neurogenesis. Endogenous neural progenitor ...
Speech Preservation during Language-dominant, Left Temporal Lobe Seizures: Report of a Rare, Potentially Misleading Finding
(Blackwell Publishing Inc, 2006-08)
Purpose: To evaluate the prevalence and mechanism of ictal speech in patients with language-dominant, left temporal lobe seizures. Methods: We retrospectively reviewed the video-EEG telemetry records for the presence of ...
Measurement of progression in Alzheimer's disease: a clinician's perspective
(John Wiley & Sons, Ltd., 2000-06-15)
Patients with Alzheimer's disease (AD) and their families must confront two fundamental truths. First, AD is a uniformly progressive disease that ultimately results in debilitating cognitive impairment. Second, although ...
Serial Cognitive Testing in Temporal Lobe Epilepsy: Longitudinal Changes with Medical and Surgical Therapies
(Blackwell Publishing Ltd, 1994-07)
Cognitive testing was repeated at intervals ranging from 1 to 8 years in 47 adult patients with temporal lobe epilepsy (TLE). Each patient underwent standardized batteries, including the Wechsler Adult Intelligence Scale, ...
A Clinical Trial of Gene Therapy for Chronic Pain
(Blackwell Publishing Inc, 2009-10)
The first human trial of gene therapy for chronic pain, a phase 1 study of a nonreplicating herpes simplex virus (HSV)-based vector engineered to express preproenkephalin in patients with intractable pain from cancer, began ...
Identification of proteins in human substantia nigra
(WILEY-VCH Verlag, 2008-05)
Characterization of the human brain proteome is a critical area of research. While examination of the human cortex has provided some insight, very little is known about the proteome of the human midbrain, which demonstrates ...
Neuropsychological Deficits Are Correlated with Frontal Hypometabolism in Positron Emission Tomography Studies of Older Alcoholic Patients
(Blackwell Publishing Ltd, 1993-04)