Now showing items 1-10 of 23
A quantitative study of retrograde axonal transport in motor and sensory neurons
(Elsevier, 1986-04)
We used 3H N-succinimidyl propionate to covalently label in vivo proteins of the rat sciatic nerve, and studied the accumulation of radioactively labeled proteins in the cell bodies of the ipsilateral dorsal root ganglion ...
Calmodulin distribution in peripheral nerve: an EM immunocytochemical study
(Elsevier, 1988-12-20)
We used electron microscopic immunocytochemistry to study the distribution of calmodulin in rat sciatic nerve. Calmodulin immunoreactivity was found throughout the axoplasmic matrix, but particularly along microtubules. ...
A signal generator for testing extracellular recording amplifiers and probes
(Elsevier, 1988-10)
A portable signal generator that simulates the amplitude and frequency of neuronal signals for testing extracellular recording amplifiers is described. The signal generator is easy to construct and it is extremely useful ...
Histological localization of binding sites of [alpha]-bungarotoxin and of antibodies specific to acetylcholine receptor in goldfish optic nerve and tectum
(Elsevier, 1980-07-21)
Goldfish optic nerve as well as ganglion cell neurites grown in culture selectively bind rhodamine-labeled [alpha]-bungarotoxin following tissue fixation. Binding is competed for by unlabeled bungarotoxin, by carbamylcholine ...
A sequential double-label autoradiographic method that quantifies altered rates of regional glucose metabolism
(Elsevier, 1985-12-30)
An autoradiographic sequential double-label variant of the deoxyglucose method for measurement of local glucose utilization has been developed. This technique takes advantage of the short half-life of the positron emitter, ...
A densitometer for quantitative autoradiography
(Elsevier, 1983-11)
A low cost spot densitometer system is described. This system is useful for quantitative autoradiography of local cerebral glucose utilization, blood flow, receptor binding and other applications requiring densitometry on ...
Glutamate transmission and toxicity in alzheimer's disease
(Elsevier, 1988)
1. 1. Despite intensive research, the cause of Alzheimer's disease is unknown.2. 2. Glutamate is the major excitatory transmitter of the cerebral cortex and hippocampus and it appears to have an important role in learning ...
Changes in intra-axonal calcium distribution following nerve crush
(Wiley Subscription Services, Inc., A Wiley Company, 1986-09)
We used the oxalate-pyroantimonate method to demonstrate the ultrastructural distribution of calcium within rat sciatic nerve 4 h after a crush injury. In normal nerve there are discrete gradients of axoplasmic calcium ...
Effects of excitotoxic striatal lesions on single unit activity in globus pallidus and entopeduncular nucleus of the cat
(Elsevier, 1989-11-06)
Striatal projections to the globus pallidus and entopeduncular nucleus are thought to be GABAergic and inhibitory. Thus, striatal lesions might be expected to increase the spontaneous discharge rate of neurons in these ...
Enhancing high-speed digitization of single-unit neuronal activity on a microcomputer using a hybrid software-hardware technique
(Elsevier, 1989-06)
A new data acquisition technique allows a microcomputer simultaneously to digitize spikes at high rates, analyze spike waveforms for computer-based spike separation and manage other control tasks. The technique has two key ...