Now showing items 1-10 of 37
Transtubular bioreactor: A perfusion device for mammalian cell cultivation
(Kluwer Academic Publishers; Science & Technology Letters ; Springer Science+Business Media, 1989-01)
A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied ...
Synthesis and Erosion Properties of PEG-Containing Polyanhydrides
(WILEY-VCH Verlag, 2007-05-10)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis( p -carboxyphenoxy)propane and poly(ethylene glycol) were ...
Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide
(Elsevier, 1989)
Previous studies have demonstrated that a number of membrane-active agents are capable of binding to the surface of polymorphonuclear leukocytes (PMN) resulting in an augmentation of superoxide anion and hydrogen peroxide ...
Transferrin: A potential source of iron for oxygen free radical-mediated endothelial cell injury
(Elsevier, 1992-04)
The ability of transferrin to potentiate oxygen free radical-mediated endothelial cell injury was assessed. 51Cr-labeled endothelial cells derived from rat pulmonary arteries (RPAECs) were incubated with hydrogen peroxide ...
Oxygen radicals in complement and neutrophil-mediated acute lung injury
(Elsevier, 1985)
The development of experimental acute lung injury following systemic complement activation is closely related to availability of blood neutrophils. Although tissue-destructive neutrophil-derived may play a supportive role ...
Interaction of viable group a streptococci and hydrogen peroxide in killing of vascular endothelial cells
(Elsevier, 1993-05)
Previous studies have shown that the streptococcal hemolysin, streptolysin S, is capable of interacting with hydrogen peroxide (H2O2) to injure vascular endothelial cells (Free Radic. Biol. Med. 7:369-376; 1989). To extend ...
Inhibition of hypochlorous acid-mediated reactions by desferrioxamine. Implications for the mechanism of cellular injury by neutrophils
(Elsevier, 1990)
Inhibition of free radical mechanisms by desferrioxamine, an iron chelator, is often thought to be a good indicator of iron-catalyzed hydroxyl radical (OH[middle dot]) production. The specificity of desferrioxamine is ...
Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors
(Elsevier, 1982-12)
Mononuclear phagocytes are knwon to play a key role in various phlogistic reactions by synthesizing and releasing products that may potentiate or inhibit inflammatory processes. The expression of these products appears to ...
Chromogranin from normal human adrenal glands: purification by monoclonal antibody affinity chromatography and partial N-terminal amino acid sequence
(Elsevier, 1986-02)
A method is presented for the purification of human chromogranin from adrenal glands obtained at autopsy. The procedure involved homogenization of whole glands in aqueous buffer, salt precipitation, affinity chromatography ...
The role of oxygen radicals in immune complex injury
(Elsevier, 1988)
In this review we will summarize our current understanding of the mediation of immune complex induced tissue injury. Comparisons will be made between the mediation of IgG versus IgA immune complex injury with emphasis on ...