Now showing items 21-30 of 51
Improved prognosis of intracranial non-germinoma germ cell tumors with multimodality therapy
(Kluwer Academic Publishers; Springer Science+Business Media, 1997-03)
The 5 year survival for patients with malignant intracranial non-germinoma germ cell tumors (NGGCT) which include endodermalsinus tumors, embryonal carcinomas, choriocarcinomas and immatureteratomas is less than 25% following ...
Interferon-Γ inhibits DNA synthesis and insulin-like growth factor-II expression in human neuroblastoma cells
(Wiley Subscription Services, Inc., A Wiley Company, 1993-04-01)
Interferon-Γ (IFN-Γ) is known to be an antiproliferative, differentiation agent in many cell types, including neuroblastoma. In this study, we determined the effects of IFN-Γ on cellular growth and expression of insulin-like ...
Developmental changes in the expression of chemokine receptor CCR1 in the rat cerebellum
(Wiley Subscription Services, Inc., A Wiley Company, 2003-02-24)
Chemokines are small, soluble proteins that regulate leukocyte migration, adhesion, and proliferation. Recent evidence suggests that chemokine receptors are expressed in the central nervous system and that their functions ...
Excitotoxic Brain Injury Suppresses Striatal High-Affinity Glutamate Uptake in Perinatal Rats
(Blackwell Publishing Ltd, 1991-03)
In immature rodent brain, the glutamate receptor agonist N -methyl-D-aspartate (NMDA) is a potent neurotoxin. In postnatal day (PND)-7 rats, intrastriatal injection of 25 nmol of NMDA results in extensive ipsilateral ...
Concentrations of Homovanillic Acid and 5-Hydroxyindoleacetic Acid in Cerebrospinal Fluid from Human Infants in the Perinatal Period
(Blackwell Publishing Ltd, 1984-12)
To assess maturation of central serotonin and catecholamine pathways at birth, we measured lumbar CSF homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), stable acid metabolites of dopamine and serotonin, using ...
Pulsatile LH secretion in women with premenstrual syndrome (PMS): Evidence for normal neuroregulation of the menstrual cycle
(Elsevier, 1992)
The premenstrual syndrome (PMS) has been proposed to result from excessive exposure to and/or withdrawal of brain opioid activity during the luteal phase. Because hypothalamic opioids are believed to modulate GnRH secretion, ...
Resistance to nitroprusside neurotoxicity in perinatal rat brain
(Elsevier, 1994-05-19)
Nitric oxide (NO) may mediate some of the toxic effects of the excitatory amino acid (EAA) glutamate when there is overactivation of the (NMDA) receptor. In the developing rodent nervous system, NMDA neurotoxicity peaks ...
Kinetics of Radiolabeled Adrenocorticotropin Hormone in Infant and Weanling Rats
(Blackwell Science Ltd, 1997-07)
Atypical Presentations of Spinal Cord Tumors in Children
(Sage Publications, 1992)
Pain is a frequent presenting symptom of spinal cord tumors in children and usually manifests as local spinal pain in the bony segments overlying the tumor. Two pediatric patients are presented in whom the diagnosis of ...