Now showing items 1-10 of 16
Gene expression of the insulin-like growth factors and their receptors in cultured human retinal pigment epithelial cells
(Elsevier, 1992-01)
Insulin-like growth factors I and II (IGF I and II) are polypeptides with both growth-promoting and insulin-like metabolic effects16,27. Immunoreactive IGF I is present in the retina14 and both IGF I and II are present in ...
Short-Term Adrenalectomy Increases Glucocorticoid and Mineralocorticoid Receptor mRNA in Selective Areas of the Developing Hippocampus
(Elsevier, 1993-10)
In the central nervous system, adrenal steroids bind to two different types of corticosteroid receptors: glucocorticoid (GR) or mineralocorticoid (MR). In vitro biochemical and autoradiographic techniques have been used ...
Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines
(Elsevier, 1992-10)
Insulin-like growth factors (IGF) I and II are polypeptides with both growth-promoting and insulin-like metabolic effects. The developmentally specific expression of IGF I and II in the nervous system implies a role for ...
Magnesium reduces (NMDA)-mediated brain injury in perinatal rats
(Elsevier, 1990-02-05)
We evaluated the neuroprotective effects of systemically administered magnesium against (NMDA)-mediated brain injury in perinatal rats. Postnatal day (PND) 7 rats received unilateral intrastriatal injections of 25 nmol ...
The microsomal calcium-ATPase inhibitor thapsigargin is a neurotoxin in perinatal rodent brain
(Elsevier, 1992-10-12)
Thapsigargin is a potent inhibitor of the microsomal calcium-ATPase. We hypothesized that thapsigargin-induced liberation of calcium from sequestered intracellular sites could result in irreversible brain injury. To assess ...
MK-801 pretreatment enhances brain injury and increases brain recognition site binding in rats
(Elsevier, 1990)
Direct intracerebral administration of typically produces focal brain injury. (+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-immine maleate (MK-801), a non-competitive antagonist, can protect against -mediated ...
Effect of depolarization on striatal amino acid efflux in perinatal rats: An in vivo microdialysis study
(Elsevier, 1991-07-08)
We used in vivo microdialysis to determine if infusion of depolarizing concentrations of potassium stimulated striatal excitatory amino acid (EAA) efflux in post-natal day (PND) 7 rats. Dialysis probes were perfused with ...
Expression of Corticotropin-Releasing Hormone Transgenes in Neurons of Adult and Developing Mice
(Elsevier, 1994-12)
The DNA sequences important for cell-specific expression and developmental regulation of corticotropin-releasing hormone (CRH) were analyzed in transgenic mice. A construct containing 0.5 kb of CRH 5' flanking DNA linked ...
Accumulated glutamate levels in the synaptic vesicle are not maintained in the absence of active transport
(Elsevier, 1990-03-14)
We have investigated factors which may affect accumulated glutamate levels in synaptic vesicles and glutamate efflux. Agents which dissipate the electrochemical proton gradient resulted in a rapid reduction of steady-state ...
A cellular wireless local area network with QoS guarantees for heterogeneous traffic
(Kluwer Academic Publishers; Springer Science+Business Media, 1998-03)
A wireless local area network (WLAN) or a cell with quality‐of‐service (QoS) guarantees for various types of traffic is considered. A centralized (i.e., star) network is adopted as the topology of a cell which consists of ...