Now showing items 21-30 of 72
Platelet alpha2 adrenoreceptors are decreased in number after antidepressant therapy
(Elsevier, 1983)
1. 1. Specific binding of 3H-clonidine to alpha2 adrenoreceptors upon human blood platelet membranes is increased in patients with major depressive disorder (endogenous depression).2. 2. Specific binding of 3H-yohimbine ...
Glutamate Uptake into Synaptic Vesicles: Competitive Inhibition by Bromocriptine
(Blackwell Publishing Ltd, 1989-12)
The ATP-dependent uptake of l-glutamate into synaptic vesicles has been well characterized, implicating a key role for synaptic vesicles in glutamatergic neurotransmission. In the present study, we provide evidence that ...
Muscarinic Receptors in Chromaffin Cell Cultures Mediate Enhanced Phospholipid Labeling but Not Catecholamine Secretion
(Blackwell Publishing Ltd, 1981-08)
The addition of either carbachol or muscarinic agonists to cultured bovine adrenal chromaffin cells results in a selective stimulation of phosphatidate (PhA) and phosphatidylinositol (PhI) labeling from 32 P i and [ 3 ...
Isolated Light Chain of Tetanus Toxin Inhibits Exocytosis: Studies in Digitonin-Permeabilized Cells
(Blackwell Publishing Ltd, 1989-09)
Previous work indicates that the heavy chain of tetanus toxin is responsible for the binding of the toxin to the neuronal membrane and its subsequent internalization. In the present study, the light chain of tetanus toxin ...
Distribution of Protein I, a Synapse-Specific Phosphoprotein, and Adenylate Cyclase in the Rat Spinal Cord
(Blackwell Publishing Ltd, 1981-01)
The longitudinal and transverse distributions of the synapse-specific phosphoprotein Protein I and adenylate cyclase in the rat spinal cord were studied. Protein I was found to be enriched in all cervical and midlumbar (L ...
Behavior maintained by intravenous injection of codeine, cocaine, and etorphine in the rhesus macaque and the pigtail macaque
(Springer-Verlag, 1980-10)
Lever-pressing behavior of two species of macaque, the rhesus macaque ( M. mulatta ) and the pigtail macaque ( M. nemestrina ) was maintained by intravenous injection of codeine, etorphine, or cocaine. Monkeys responded ...
Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues
(Blackwell Publishing Ltd, 1987-04)
Similarity of the discriminative stimulus effects of ketamine, cyclazocine, and dextrorphan in the pigeon
(Springer-Verlag, 1981-05)
Separate groups of pigeons were trained to discriminate the IM injection of ketamine, cyclazocine, or dextrorphan from saline. Each of the training drugs and phencyclidine produced dose-related, drug-appropriate responding ...
Comparison of acute and chronic lithium treatment on 3 H-norepinephrine uptake by rat brain slices
(Springer-Verlag, 1980-01)
The effects of lithium chloride, given IP in high (2.5–15 mEq/kg) and low (1.25 mEq/kg) doses twice daily, upon 3 H-norepinephrine uptake and retention were examined with slices from four regions of the rat brain, namely ...