Now showing items 31-40 of 72
Electrophysiological responsiveness to isoproterenol in rat hippocampal slices correlates with changes in [beta]-adrenergic receptor density induced by chronic morphine treatment
(Elsevier, 1989-04-17)
The effects of chronic morphine treatment and morphine withdrawal on [beta]-adrenergic receptor density and electrophysiological responsiveness in rat hippocampus were examined. Chronic treatment of rats with morphine for ...
Relationship Between Ca 2+ Uptake and Catecholamine Secretion in Primary Dissociated Cultures of Adrenal Medulla
(Blackwell Publishing Ltd, 1982-09)
Carbachol or elevated K + stimulated 45 Ca 2+ uptake into chromaffin cells two- to fourfold. The uptake was stimulated by cholinergic drugs with nicotinic activity, but not by those with only muscarinic activity. Ca 2+ ...
The effects of antidepressants on the retention and metabolism of [3H]-norepinephrine in rat brain slices
(Elsevier, 1981-04)
Tricylic antidepressants acutely decrease the neuronal retention of [3H]-norepinehrine ([3H]-NE) by blocking neuronal membrane uptake and/or vesicular uptake and binding. To distinguish between effects upon the plasma ...
Interaction of synthetic opioid metenkephalin peptide analogs, lilly 127623 and FK 33-824 with indole hallucinogens: Antagonism of N,N-dimethyltryptamine- and LSD-induced disruption of food-rewarded bar pressing behavior in the rat
(Springer-Verlag, 1983-07)
The selected opioid metenkephalin synthetic peptide analogs Lilly (LY) 127623 and FK 33-824 were tested for behavioral dose effects and potential interaction with N,N-dimethyltryptamine (DMT) and lysergic acid diethylamide-25 ...
A Putative M 3 Muscarinic Cholinergic Receptor of High Molecular Weight Couples to Phosphoinositide Hydrolysis in Human SK-N-SH Neuroblastoma Cells
(Blackwell Publishing Ltd, 1988-03)
The M 1 -selective (high affinity for pirenzepine) muscarinic acetylcholine receptor (mAChR) antagonist pirenzepine displaced both N -[ 3 H]methylscopolamine ([ 3 H]NMS) and [ 3 H]qui-nuclidinylbenzilate from intact human ...
Effects of selected opioid agonists and antagonists on DMT-and LSD-25-induced disruption of food-rewarded bar pressing behavior in the rat
(Springer-Verlag, 1981-11)
Several opioid agonists and antagonists interact with N,N-dimethyltryptamine (DMT) and lysergic acid diethylamide-25 (LSD) in adult male Holtzman rats trained on a positive reinforcement, fixed ratio 4 (FR 4 ) behavioral ...
Fluphenazine-induced acute and tardive dyskinesias in monkeys
(Springer-Verlag, 1984-09)
Five Cebus apella monkeys were treated with biweekly injections of fluphenazine enanthate (0.1–3.2 mg/kg IM). Three of these completed 1 full year of treatment, one injured its leg after 6 months of treatment and was killed, ...
Inhibition of a Low K m GTPase Activity in Rat Striatum by Calmodulin
(Blackwell Publishing Ltd, 1985-02)
In rat striatum, the activation of adenylate cyclase by the endogenous Ca 2+ -binding protein, calmodulin, is additive with that of GTP but is not additive with that of the nonhydrolyzable GTP analog, guanosine-5′-(Β, ...
Arachidonic Acid Release and Catecholamine Secretion from Digitonin-Treated Chromaffin Cells: Effects of Micromolar Calcium, Phorbol Ester, and Protein Alkylating Agents
(Blackwell Publishing Ltd, 1985-01)
The relationship between catecholamine secretion and arachidonic acid release from digitonin-treated chromaffin cells was investigated. Digitonin renders permeable the plasma membranes of bovine adrenal chromaffin cells ...
Differential Regulation by Calmodulin of Basal, GTP-, and Dopamine-Stimulated Adenylate Cyclase Activities in Bovine Striatum
(Blackwell Publishing Ltd, 1988-08)
The concentration requirements of calmodulin in altering basal, GTP-, and dopamine-stimulated adenylate cyclase activities in an EGTA-washed paniculate fraction from bovine striatum were examined. In the bovine striatal ...