Now showing items 31-40 of 75
Electrophysiologic actions and antifibrillatory efficacy of subacute left stellectomy in a conscious, post-infarction canine model of ischemic ventricular fibrillation
(Elsevier, 1989-03)
The autonomic nervous system appears to modulate ventricular arrhythmias associated with acute myocardial ischemia. This study investigated the electrophysiologic effects and antifibrillatory actions of subacute left ...
Myocardial ischemia, reperfusion and free radical injury
(Elsevier, 1990-05-22)
Reperfusion of coronary arteries to limit myocardial ischemic injury and extent of myocardial necrosis is possible by either the use of fibrinolytic therapy, coronary angioplasty or coronary artery bypass surgery. The ...
Absence of detectable xanthine oxidase in human myocardium
(Elsevier, 1989-03)
The enzyme xanthine oxidase has been implicated as a generator of toxic oxygen metabolites that contribute to ischemic injury. Because substantial species variability has been demonstrated and because there are minimal ...
Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice Potential conflict of interest: Nothing to report.
(Wiley Subscription Services, Inc., A Wiley Company, 2009-07)
Steatosis in the liver is a common feature of obesity and type 2 diabetes and the precursor to the development of nonalcoholic steatohepatitis (NASH), cirrhosis, and liver failure. It has been shown previously that inhibiting ...
Rationale of therapy in the patient with acute myocardial infarction and life-threatening arrhythmias: A focus on bretylium
(Elsevier, 1984-07-30)
Experimental evidence suggests a number of pathologic and electrophysiologic mechanisms that may help initiate ventricular arrhythmias accompanying myocardial ischemia and infarction. Early and late phase events are ...
The anti-fibrillatory effect of dimethyl quaternary propranolol (UM-272)
(Elsevier, 1973-01)
Cardiac electrophysiologic interactions of bepridil, a new calcium antagonist, with enflurane, halothane, and isoflurane
(Elsevier, 1988-06)
Bepridil is an investigational calcium antagonist that also has fast sodium channel blocking and antidysrhythmic properties. In the present study, the potential interactions of bepridil with volatile anesthetics on cardiac ...
Thromboxane synthetase inhibition with CGS 13080 improves coronary blood flow after streptokinase-induced thrombolysis
(Elsevier, 1987-06)
The focus of this investigation was to examine the potential beneficial effects of the selective thromboxane synthetase inhibitor CGS 13080 (imidazo [1,5-a] pyridine-5-hexanoic acid) on coronary blood flow after ...
GREB1 is a critical regulator of hormone dependent breast cancer growth
(Kluwer Academic Publishers; Springer, 2005-07)
Background Estrogen plays a central role in breast cancer pathogenesis and many potent risk factors for the development of the disease can be explained in terms of increased lifetime exposure to estrogen. Although estrogen ...
Cardioprotective effects of amlodipine in the ischemic-reperfused heart
(Elsevier, 1989-11)