Now showing items 21-30 of 88
Psychotropic drug influences on brain acetylcholine utilization
(Springer-Verlag, 1972-12)
The cholinergic antisynthesis agent HC-3 was given intraventricularly to young male rats 20–30 days old to deplete brain acetylcholine (ACh). The rate of HC-3 induced depletion of ACh was used as an index of ACh utilization. ...
Effects of psychoactive agents on acquisition of conditioned pole jumping in rats
(Springer-Verlag, 1965-07)
Albino rats required progressively more trials to reach a 90 percent avoidance criterion and achieved less mean total percent avoidance learning than saline injected controls following administration of increasing doses ...
Effects of chronic and acute treatment of antipsychotic drugs on calmodulin release from rat striatal membranes
(Elsevier, 1980-03)
Chronic treatment of rats with the antipsychotic drugs haloperidol and (+)-butaclamol results in supersensitivity of striatal dopamine (DA) receptors. Striatal membranes of these animals have an increased content of an ...
Convulsant activity of a non-peptidic δ-opioid receptor agonist is not required for its antidepressant-like effects in Sprague-Dawley rats
(Springer-Verlag, 2002-10)
Abstract
Effects of various psychotomimetic agents on the eeg and acetylcholine release from the cerebral cortex of brainstem transected cats
(Elsevier, 1972-09)
The effects of i.v. administration of [Delta]9 THC, phencyclidine, the pyrrolidyl and piperidyl isomers of Ditran, and LSD-25 were determined on the spontaneous neocortical EEG and release of acetylcholine (ACh) from the ...
Nicotine-induced eeg and behavioral arousal,
(Elsevier, 1965-11)
(-) Nicotine, in doses of 0.005-0.01 mg/kg given intravenously over 1 min, produced transient behavioral arousal and EEG activation in cats with chronic indwelling brain electrodes. The effects of nicotine were evident ...
Behavioral variables affecting the development of amphetamine tolerance
(Springer-Verlag, 1966-01)
The behavioral effects of chronic administration of d-amphetamine in rats at a dosage of 1 mg/kg were studied with baselines involving either food or shock reinforcement. Food reinforcement was assigned according to a fixed ...
Neuronal mechanisms of ketamine-induced anesthesia
(Elsevier, 1968-11)
The sites of action of ketamine (CI-581; 2-(0-chlorophenyl)-2-methylamino cyclohexamine HCl) were determined in the central nervous system using electrophysiological techniques in both acute and chronic cat experiments. ...
Discriminative stimulus effects of a centrally administered, delta-opioid peptide ( d -Pen 2 - d -Pen 5 -enkephalin) in pigeons
(Springer-Verlag, 1996-10)
The present study assessed the discriminative stimulus effects of the delta-opioid agonist [ d -Pen 2 - d -Pen 5 ]enkephalin (DPDPE) in pigeons. Food-restricted pigeons were trained to discriminate between ICV injections ...
Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay
(Springer-Verlag, 1994-07)
The opioid antagonist effects of systemically administered nor-binaltorphimine (nor-BNI) were evaluated against the kappa agonists CI-977, U69,593, U50,488, ethylketocyclazocine (EKC), Mr2034 and bremazocine, the mu agonist ...