Now showing items 11-17 of 17
Asymmetric cross-sensitization to the locomotor stimulant effects of phencyclidine and MK-801,
(Elsevier, 1994-08)
Chronic administration of a psychomotor stimulant has been shown to produce progressively enhanced effects, a phenomenon called "reverse tolerance" or sensitization. Sensitization which develops to the psychomotor stimulant ...
Immunohistochemical studies on synapse formation by embryonic cerebellar tissue transplanted into the cerebellum of the weaver mutant mouse
(Elsevier, 1987-08-31)
Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable ...
Quantitative autoradiography of [3H]sulpiride binding sites in rat brain
(Elsevier, 1984-09-28)
A technique has been developed to investigate [3H]sulpiride binding in rat brain sections using quantitative autoradiography and tritium-sensitive film. Binding was saturable and reversible with very low nonspecific binding. ...
Subcellular distributions of calcium/calmodulin-stimulated and guanine nucleotide-regulated adenylate cyclase activities in the cerebral cortex
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1986-03)
The subcellular distribution of Ca 2+ /calmodulin-stimulated adenylate cyclase activity was studied in comparison with that of guanine nucleotide-stimulated cyclase activity. The distributions of these activities were ...
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells
(Elsevier, 1992-01)
In SK-N-SH human neuroblastoma cells, the muscarinic agonist carbachol promotes polyphosphoinositide (PPI) hydrolysis via M3 receptors and increases cyclic AMP levels through an unidentified mechanism. Activation of PPI ...
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
(Elsevier, 1993-12)
Repeated, intermittent treatment of rats with amphetamine results in a sensitization of locomotor and stereotyped behaviors that is accompanied by an enhancement in stimulus-induced dopamine release. Increased phosphorylation ...
Calcium-dependent release of accumulated glutamate from synaptic vesicles within permeabilized nerve terminals
(Elsevier, 1991-01-28)
We have studied glutamate release from synaptic vesicles in permeabilized synaptosomes, which were preloaded with [3H]glutamate in an ATP-dependent manner. The release was found to be calcium-dependent and to require a ...