Now showing items 21-30 of 35
Immunohistochemical studies on synapse formation by embryonic cerebellar tissue transplanted into the cerebellum of the weaver mutant mouse
(Elsevier, 1987-08-31)
Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable ...
Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus
(Wiley Subscription Services, Inc., A Wiley Company, 2007-10)
Intermittent hypoxia, such as that associated with obstructive sleep apnea, can cause neuronal death and neurobehavioral dysfunction. The cellular and molecular mechanisms through which hypoxia alter hippocampal function ...
Nicotine effects on regional cerebral blood flow in awake, resting tobacco smokers
(John Wiley & Sons, Inc., 2000-12-01)
The hypothesis for this research was that regional cerebral blood flow (rCBF) would increase following nasal nicotine administration to overnight abstinent tobacco smokers in relationship to the known brain distribution ...
Simple transporter trafficking model for amphetamine-induced dopamine efflux
(Wiley Subscription Services, Inc., A Wiley Company, 2007-07)
Amphetamine and its derivatives are important drugs of abuse causing both short-term excitatory and long-term addictive effects. The short-term excitatory effects are linked to amphetamine's ability to maintain high levels ...
Alterations in calmodulin content and localization in areas of rat brain after repeated intermittent amphetamine
(Elsevier, 1991-10-18)
To assess whether calmodulin (CaM) could have a role in the behavioral sensitization induced by repeated intermittent amphetamine, CaM content was determined in several brain areas from rats repeatedly administered saline ...
Quantitative autoradiography of [3H]sulpiride binding sites in rat brain
(Elsevier, 1984-09-28)
A technique has been developed to investigate [3H]sulpiride binding in rat brain sections using quantitative autoradiography and tritium-sensitive film. Binding was saturable and reversible with very low nonspecific binding. ...
In vivo imaging of monoaminergic nerve terminals in normal and MPTP-lesioned primate brain using positron emission tomography (PET) and [ 11 C]tetrabenazine
(Wiley Subscription Services, Inc., A Wiley Company, 1993-06)
The first successful in vivo imaging of monoamine vesicular transporters in the living primate brain is described, using [ 11 C]tetrabenazine ([ 11 C]TBZ) and Positron Emission Tomography (PET). Radioligand uptake into ...
Subcellular distributions of calcium/calmodulin-stimulated and guanine nucleotide-regulated adenylate cyclase activities in the cerebral cortex
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1986-03)
The subcellular distribution of Ca 2+ /calmodulin-stimulated adenylate cyclase activity was studied in comparison with that of guanine nucleotide-stimulated cyclase activity. The distributions of these activities were ...
Extracellular calcium alters frequency modulation of [3H]acetylcholine release from rat hippocampal slices
(Elsevier, 1987-09-08)
The concentration of extracellular Ca2+ has been shown to enhance or attenuate [3H]acetylcholine (ACh) release subsequent to a conditioning stimulus in rat brain hippocampal slices. Slices were incubated in vitro in ...
Estradiol attenuates the K + -induced increase in extracellular GABA in rat striatum
(Wiley Subscription Services, Inc., A Wiley Company, 2006-02)
Estradiol acts rapidly and directly to inhibit L-type Ca 2+ current in medium spiny neurons from striatum. Since medium spiny neurons contain Γ-aminobutyric acid (GABA), we hypothesized that estradiol inhibition of Ca 2+ ...