Now showing items 1-10 of 115
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Chronic haloperidol treatment increased calcium-dependent phosphorylation in rat striatum
(Elsevier, 1982-01-04)
In previous studies, we observed that when rats were chronically treated with haloperidol, there was a significant increase of calmodulin activity in their striatal membranes. Calmodulin is knwon to modulate calcium-dependent ...
The effect of brainstem transection on blood pressure in the dog
(Elsevier, 1969-03-01)
Blood pressure was compared before and after midpontine pretrigeminal brainstem transection in the dog. Statistically significant decreases in blood pressure were observed 1/2, 1, and 1-1/2 hours after brainstem transection. ...
Further studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibody
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1983-07)
A monoclonal antibody has been obtained that recognizes an antigen encoded by human chromosome 11. We present evidence that this monoclonal antibody recognizes the same or a similar antigenic activity as that previously ...
Protein kinase C and clostridial neurotoxins affect discrete and related steps in the secretory pathway
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1993-12)
1. The effects on catecholamine secretion of activation of protein kinase C and clostridial neurotoxins were examined in digitonin-permeabilized bovine adrenal chromaffin cells.
Resolution in the receptor binding of putative [mu] and [kappa] opiates
(Elsevier, 1984-05-28)
Conditions for the stereospecific binding of 3H-ethylketocyclazocine and 3H-etorphine were established in membranes from rat and pigeon brain. In displacing the specific binding of the radiolabeled ligands, putative [mu] ...
Tidal freshwater wetland zonation: seed and seedling dynamics
(Elsevier, 1994-01)
Zonation patterns of seed rain (input), persistent seed bank (seeds persisting for 1 year or longer), field seedlings, and seed production were studied in a New Jersey tidal freshwater wetland along transects extending ...
Analysis of the Late Steps of Exocytosis: Biochemical and Total Internal Reflection Fluorescence Microscopy (TIRFM) Studies
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-04-20)
1. Time with Julie in his laboratory at the NIH in the early 1970s is remembered. The experience led to a life-long interest in the regulation of catecholamine secretion. Here are summarized aspects of this work.
Receptor binding, antagonist, and withdrawal precipitating properties of opiate antagonists
(Elsevier, 1983-06-20)
A number of opiate antagonists and the dextro isomers of some of these drugs were studied for antagonism of acute opiate effects on ilea isolated from opiate-naive guinea pigs, precipitation of a withdrawal contraction of ...
Changes in cortical [beta]-adrenergic receptor density and neuronal sensitivity to norepinephrine accompany morphine dependence and withdrawal
(Elsevier, 1987-01-01)
Radioligand binding experiments were carried out in conjunction with electrophysiological recordings in vivo in the parietal cortex in rats to assess changes in postsynaptic [beta]-adrenergic receptor function that result ...