Now showing items 1-10 of 206
Cholinergic Receptor-Mediated Phosphorylation and Activation of Tyrosine Hydroxylase in Cultured Bovine Adrenal Chromaffin Cells
(Blackwell Publishing Ltd, 1986-02)
We have identified a 56-kilodalton protein in cultured bovine adrenal chromaffin cells that is phos-phorylated when catecholamine secretion is stimulated. Immunodetection on Western blots from both one- and two-dimensional ...
β-funaltrexamine antagonizes the discriminative stimulus effects of morphine but not naltrexone in pigeons
(Springer-Verlag, 1987-02)
Antagonistic actions of the irreversible, μ-selective antagonist β-funaltrexamine (β-FNA) were evaluated in pigeons trained to discriminate among intramuscular injections of morphine (5.6 mg/kg), saline, and naltrexone ...
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Diabetic neuropathy: inhibitory G protein dysfunction involves PKC-dependent phosphorylation of G oα
(Blackwell Science Ltd, 2003-08)
We examined the hypothesis that decreased inhibitory G protein function in diabetic neuropathy is associated with increased protein kinase C (PKC)-dependent phosphorylation of the G oα subunit. Streptozotocin-induced ...
A Role for the Small Molecular Weight GTPases, Rho and Cdc42, in Muscarinic Receptor Signaling to Focal Adhesion Kinase
(Blackwell Science Ltd., 2000-05)
Short-term effects of marijuana smoking on cognitive behavior in experienced male users
(Springer-Verlag, 1973-03)
The effects of smoking marijuana on the ability to use abstract concepts was tested in 12 experienced marijuana users. Each subject was tested three times, after smoking prepared 300 mg cigarettes containing either 0, 1.5 ...
Effects of tobacco smoking on the topographic EEG I
(Elsevier, 1994-09)
1. 1. The EEG and cardiovascular effects of smoking tobacco cigarettes of varying nicotine content were studied in Japanese chronic tobacco smokers.2. 2. Thirteen female and fifteen male adult normal volunteers were recruited ...
Attachment of the Synapse-Specific Phosphoprotein Protein I to the Synaptic Membrane: A Possible Role of the Collagenase-Sensitive Region of Protein I
(Blackwell Publishing Ltd, 1981-01)
The purified synapse-specific phosphoprotein Protein I was previously shown to be degraded by a bacterial collagenase, through a series of intermediates, to a collagenase-resistant fragment of molecular weight about 48,000 ...
Endogenous Bax Translocation in SH-SY5Y Human Neuroblastoma Cells and Cerebellar Granule Neurons Undergoing Apoptosis
(Blackwell Publishing Ltd, 1999-05)
Changes at the mitochondria are an early, required step in apoptosis in various cell types. We used western blot analysis to demonstrate that the proapoptotic protein Bax translocated from the cytosolic to the mitochondrial ...
Conditional ablation and recovery of forebrain neurogenesis in the mouse
(Wiley Subscription Services, Inc., A Wiley Company, 2009-06-20)
Forebrain neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and hippocampal dentate gyrus (DG). Several strategies have been employed to eliminate adult neurogenesis and thereby determine whether ...