Now showing items 1-10 of 346
β-funaltrexamine antagonizes the discriminative stimulus effects of morphine but not naltrexone in pigeons
(Springer-Verlag, 1987-02)
Antagonistic actions of the irreversible, μ-selective antagonist β-funaltrexamine (β-FNA) were evaluated in pigeons trained to discriminate among intramuscular injections of morphine (5.6 mg/kg), saline, and naltrexone ...
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Chronic haloperidol treatment increased calcium-dependent phosphorylation in rat striatum
(Elsevier, 1982-01-04)
In previous studies, we observed that when rats were chronically treated with haloperidol, there was a significant increase of calmodulin activity in their striatal membranes. Calmodulin is knwon to modulate calcium-dependent ...
Renewed interest in the polyphosphoinositides
(Elsevier, 1984-02)
The significance of the enhanced cellular phosphatidate and phosphatidylinositol turnover which occurs in response to specific extracellular messengers has been the subject of much interest and speculation. Until recently, ...
The effect of brainstem transection on blood pressure in the dog
(Elsevier, 1969-03-01)
Blood pressure was compared before and after midpontine pretrigeminal brainstem transection in the dog. Statistically significant decreases in blood pressure were observed 1/2, 1, and 1-1/2 hours after brainstem transection. ...
Electrolysis-induced myocardial dysfunction : A novel method for the study of free radical mediated tissue injury
(Elsevier, 1986-07)
Oxygen-derived free radicals and other oxidizing species are thought to be involved in inflammation and ischemic tissue injuries. Recently, oxygen-derived free radicals also have been implicated in tissue injury of the ...
Metabolic effects of short-chain ceramide and glucosylceramide on sphingolipids and protein kinase C
(Blackwell Publishing Ltd, 1992-12)
Further studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibody
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1983-07)
A monoclonal antibody has been obtained that recognizes an antigen encoded by human chromosome 11. We present evidence that this monoclonal antibody recognizes the same or a similar antigenic activity as that previously ...
A specific radioimmunoassay for androstenedione with reduced bridge-binding
(Elsevier, 1984-09)
Antibody used in a steroid radioimmunoassay raised against a steroid hapten-carrier protein conjugate may recognize both the hapten and the chemical bridge to the protein. Use of the same bridge in the radioisotopic label ...