Now showing items 1-4 of 4
Autoradiography-based, three-dimensional calculation of dose rate for murine, human-tumor xenografts
(Elsevier, 1993-11)
A Fast Fourier Transform method for calculating the three-dimensional dose rate distribution for murine, human-tumor xenografts is outlined. The required input includes evenly-spaced activity slices which span the tumor. ...
Synthesis of a nonpeptide carbon-11 labeled substance P antagonist for PET studies
(Elsevier, 1993-05)
CP 96,345 is a nonpeptide high affinity antagonist of the substance P (NK1) receptor. The radiosynthesis of [11C]CP 96,345 suitable for Positron Emission Tomography (PET) applications is described. [11C]CP 96,345 was ...
Synthesis of the 123I- and 125I-labeled cholinergic nerve marker (-)-5-iodobenzovesamicol
(Elsevier, 1993-11)
The highly toxic curaremimetic and cholinergic neuron marker (-)-5-iodobenzovesamicol (IBVM) has been labeled with iodine-125 and iodine-123. [125I]IBVM, suitable for animal distribution and ex vivo autoradiographic studies, ...
High yield synthesis of high specific activity R-(-)-[11C]epinephrine for routine PET studies in humans
(Elsevier, 1993-11)
R-(-)-[11C]Epinephrine ([11C]EPI) has been synthesized from R-(-)-norepinephrine by direct methylation with [11C]methyl iodide or [11C]methyl triflate. The total synthesis time including HPLC purification was 35-40 min. ...