Now showing items 11-12 of 12
Co-targeting p53-R249S and CDK4 synergistically suppresses survival of hepatocellular carcinoma cells
(Taylor & Francis, 2020-03-03)
p53-R249S (p53-RS) is frequently detected in human hepatocellular carcinoma (HCC) that is highly associated with hepatitis B infection and aflatoxin B1 exposure. Our previous study showed that CDK4/Cyclin D1 phosphorylates ...
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53
(Springer Nature, 2020-01-30)
RNA-binding motif protein 10 (RBM10) is an RNA-binding protein frequently deleted or mutated in lung cancer cells. Recent reports showed that the knockdown of RBM10 in human cancer cells enhances the growth of mouse tumor ...