Now showing items 11-20 of 22
Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-12)
Background & Aims : Intestinal adaptation in short bowel syndrome (SBS) consists of increased epithelial cell (EC) proliferation as well as apoptosis. Previous microarray analyses of intraepithelial lymphocytes (IEL) gene ...
Toward high sequence coverage of proteins in human breast cancer cells using on-line monolith-based HPLC-ESI-TOF MS compared to CE MS
(WILEY-VCH Verlag, 2006-06)
A method is developed toward high sequence coverage of proteins isolated from human breast cancer MCF10 cell lines using a 2-D liquid separations. Monolithic-capillary columns prepared by copolymerizing styrene with ...
Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer
(WILEY-VCH Verlag, 2008-08)
The current study analyzed reverse phase protein arrays (RPPA) as a means to experimentally validate biomarkers in blood samples. One microliter samples of sera ( n 14= 1471), and plasma ( n 14= 1478) were serially diluted ...
Studies of Posttranslational Modifications in Spiny Dogfish Myelin Basic Protein
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2001-05)
The objective of this investigation was to determine whether nonmammalian myelin basic protein contained charge isomers resulting from extensive posttranslational modifications as seen in mammalian MBP. Four charge isomer ...
Pancreatic cancer stem cells and relevance to cancer treatments
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05-01)
Pancreatic cancer continues to be a malignancy with few therapeutic options. The majority of patients that present for an evaluation have locally advanced or metastatic disease that is incurable by surgical approaches. ...
Intercellular calcium waves in cultured enteric glia from neonatal guinea pig
(Wiley Subscription Services, Inc., A Wiley Company, 2003-05)
Enteric glia are important participants in information processing in the enteric nervous system. However, intercellular signaling mechanisms in enteric glia remain largely unknown. We postulated that intercellular calcium ...
A proteomic analysis of Psychrobacter articus 273-4 adaptation to low temperature and salinity using a 2-D liquid mapping approach
(WILEY-VCH Verlag, 2007-02)
Psychrobacter 273-4 was isolated from a 20 000–40 000–year-old Siberian permafrost core, which is characterized by low temperature, low water activity, and high salinity. To explore how 273-4 survives in the permafrost ...
Differential effects of cAMP and cGMP on in vitro epidermal cell growth
(Elsevier, 1979-04)
Primary keratinocyte cultures free of dermal fibroblasts were used to investigate the effect of varying cyclic AMP (cAMP) concentrations on epidermal cell function. Addition of 10-3, 10-4 or 10-5 M dibutyryl cAMP to plated ...
Augmentation of keratinocyte differentiation by the epidermal mitogen, 8-bromo-cAMP
(Elsevier, 1983-11)
The effect of the epidermal mitogen, 8-bromo-cAMP, on keratinocyte differentiation was studied. A 3 x 10-4 M dose of 8-bromo-cAMP was added to primary neonatal mouse epidermal keratinocyte cultures that slowly proliferate, ...
Stimulation of myenteric plexus neurite outgrowth by insulin and insulin-like growth factors I and II
(Elsevier, 1992)
A defined culture medium containing insulin, insulin-like growth factor I (IGF-I) or insulin-like growth II (IGF-II) supported morphological development of myenteric plexus neurons derived from neonatal guinea pigs. Insulin ...