Now showing items 1-10 of 52
Efficacy of sentinel lymph node biopsy in male breast cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2004-05-01)
Background Sentinel lymph node biopsy (SLNB) is rapidly becoming the standard of care in the treatment of women with early stage breast cancer. Male breast cancer although relatively rare, has typically been treated with ...
Induction of glutathione S -transferase-Π in Barrett's metaplasia and Barrett's adenocarcinoma cell lines
(John Wiley & Sons, Inc., 1999-02)
Barrett's metaplasia consists of columnar epithelium that replaces the normal esophageal mucosa in patients with chronic gastroesophageal reflux. Because intestinal-type Barrett's metaplasia is the major risk factor for ...
Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity
(Springer-Verlag; The Society of Surgical Oncology, Inc., 2004-01)
Background: Local, sustained delivery of cytokines at a tumor can enhance induction of antitumor immunity and may be a feasible neoadjuvant immunotherapy for breast cancer. We evaluated the ability of intratumoral ...
Mitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocols
(Steinkopff-Verlag; Dr. Dietrich Steinkopff Verlag ; Springer Science+Business Media, 1981-05)
Dog hearts were made globally ischemic for 1 hr at normothermia, at 28°C, or at normothermia after perfusion with a hyperkalemic cardioplegia solution. After 1 hr of reperfusion mitochondria were isolated from each heart ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...
Thyroid Cancer: 1999 Update and Evaluation of Solitary Thyroid Nodules
(Springer-Verlag; The Society of Surgical Oncology, Inc., 2000-04)
Is there a benefit to sentinel lymph node biopsy in patients with T4 melanoma?
(Wiley Subscription Services, Inc., A Wiley Company, 2009-12-15)
BACKGROUND: Controversy exists as to whether patients with thick (Breslow depth >4 mm), clinically lymph node-negative melanoma require sentinel lymph node (SLN) biopsy. The authors examined the impact of SLN biopsy on ...
Allogeneic and Autologous Melanoma Vaccines: Where have we been and where are we going?
(2006-04)
The past three decades have seen substantial research on vaccines for the treatment of metastatic melanoma and the prevention of recurrence following resection. Despite their enormous promise, the actual results have been ...
Distal chromosome 17q loss in Barrett's esophageal and gastric cardia adenocarcinomas: Implications for tumorigenesis
(John Wiley & Sons, Inc., 1998-08)
The molecular genetic mechanisms underlying esophageal cancer are poorly understood. However, a novel gene that may be involved in esophageal carcinogenesis was recently localized by others to distal 17q by linkage analysis ...