Now showing items 41-50 of 52
Sentinel lymph node biopsy for breast cancer: How many nodes are enough?
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-01)
Introduction Sentinel lymph node (SLN) biopsy using blue dye and radioisotope often results in the removal of multiple SLNs. We sought to determine whether there is a point where the surgeon can terminate the procedure ...
Immunologic response to cryoablation of breast cancer
(Kluwer Academic Publishers; Springer, 2005-03)
Purpose .With improvements in breast imaging and image-guided interventions, there is interest in ablative techniques for breast cancer. Cryosurgery initiates inflammation and leaves tumor-specific antigens intact, which ...
Constitutive activation of pp125fak in newly isolated human breast cancer cell lines
(Kluwer Academic Publishers; Springer Science+Business Media, 1999-03)
Our laboratory has developed twelve human breast cancer cell lines from primary and metastatic sites. In this report we demonstrate that eight of eight breast cancer cell lines examined exhibit constitutively tyrosine ...
The role of the surgeon in the management of melanoma.
(2006)
While multimodality therapy has become the standard for most solid tumors, the mainstay of therapy for melanoma remains surgical. This includes not only early stage disease, but advanced melanoma as well. The surgical ...
Is mammography useful in screening for local recurrences in patients with TRAM flap breast reconstruction after mastectomy for multifocal DCIS?
(Springer-Verlag; The Society of Surgical Oncology, Inc., 1998-07)
Background: Skin-sparing mastectomy with immediate transverse rectus abdominis musculocutaneous (TRAM) flap reconstruction is being used more often for the treatment of breast cancer. Mammography is not used routinely to ...
Is there a role for sentinel lymph node biopsy in the management of sarcoma?
(Elsevier, 2003)
Is there a role for sentinel lymph node (SLN) biopsy in the management of sarcoma? Sentinel node biopsy has dramatically
changed the management of melanoma and breast cancer, helping surgeons avoid radical lymphadenectomies ...
Neoadjuvant intratumoral cytokine-loaded microspheres are superior to postoperative autologous cellular vaccines in generating systemic anti-tumor immunity
(Wiley Subscription Services, Inc., A Wiley Company, 2006-10-01)
Background Sustained intratumoral cytokine release using poly-lactic acid microspheres (PLAMs) can induce a systemic immune response, shifting immunotherapy to the neoadjuvant setting. Methods C57BL6 mice with established ...
Is There A Role for Adjuvant High Dose Interferon in the Management of Melanoma
(Adis, 2003)
The knowledge that melanoma is susceptible to attack by the host’s immune system has resulted in the testing of a variety of immunotherapies. Interferon- α-2b, which has several anti-tumour mechanisms including an ...
Clinicopathologic features of metastasis in nonsentinel lymph nodes of breast carcinoma patients
(Wiley Subscription Services, Inc., A Wiley Company, 2003-12-01)
BACKGROUND In breast carcinoma patients with a positive sentinel lymph node (SN), the value of complete axillary lymph node dissection has been questioned. Multiple published reports have attempted to identify clinicopathologic ...
Current state of treatment for primary cutaneous melanoma.
(2004)
The incidence of malignant melanoma has been rising steadily for the last 30 years. Through physician and patient education, surveillance of high-risk individuals, and biopsy of any suspicious lesions, more lesions are ...